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The mGluR5 positive allosteric modulator VU0409551 improves synaptic plasticity and memory of a mouse model of Huntington's disease.
Doria JG, de Souza JM, Silva FR, Olmo IG, Carvalho TG, Alves-Silva J, Ferreira-Vieira TH, Santos JT, Xavier CQS, Silva NC, Maciel EMA, Conn PJ, Ribeiro FM. Doria JG, et al. Among authors: de souza jm. J Neurochem. 2018 Oct;147(2):222-239. doi: 10.1111/jnc.14555. Epub 2018 Sep 11. J Neurochem. 2018. PMID: 30028018 Free PMC article.
Metabotropic glutamate receptor 5 knockout rescues obesity phenotype in a mouse model of Huntington's disease.
Santos RPM, Ribeiro R, Ferreira-Vieira TH, Aires RD, de Souza JM, Oliveira BS, Lima ALD, de Oliveira ACP, Reis HJ, de Miranda AS, Vieira EML, Ribeiro FM, Vieira LB. Santos RPM, et al. Among authors: de souza jm, de miranda as, de oliveira acp. Sci Rep. 2022 Apr 4;12(1):5621. doi: 10.1038/s41598-022-08924-4. Sci Rep. 2022. PMID: 35379852 Free PMC article.
242 results