Smith DP - Search Results

1

Recapitulating Parkinson's disease pathology in a three-dimensional human neural cell culture model.

Taylor-Whiteley TR, Le Maitre CL, Duce JA, Dalton CF, Smith DP. Taylor-Whiteley TR, et al. Among authors: smith dp. Dis Model Mech. 2019 Apr 9;12(4):dmm038042. doi: 10.1242/dmm.038042. Dis Model Mech. 2019. PMID: 30926586 Free PMC article.

2

Linker histone H1 binds to disease associated amyloid-like fibrils.

Duce JA, Smith DP, Blake RE, Crouch PJ, Li QX, Masters CL, Trounce IA. Duce JA, et al. Among authors: smith dp. J Mol Biol. 2006 Aug 18;361(3):493-505. doi: 10.1016/j.jmb.2006.06.038. Epub 2006 Jul 3. J Mol Biol. 2006. PMID: 16854430

3

Binding of Dopamine to Alpha-Synuclein is Mediated by Specific Conformational States.

Illes-Toth E, Dalton CF, Smith DP. Illes-Toth E, et al. Among authors: smith dp. J Am Soc Mass Spectrom. 2013 Sep;24(9):1346-54. doi: 10.1007/s13361-013-0676-z. Epub 2013 Jul 2. J Am Soc Mass Spectrom. 2013. PMID: 23817832 Free PMC article.

4

Distinct higher-order α-synuclein oligomers induce intracellular aggregation.

Illes-Toth E, Ramos MR, Cappai R, Dalton C, Smith DP. Illes-Toth E, et al. Among authors: smith dp. Biochem J. 2015 Jun 15;468(3):485-93. doi: 10.1042/BJ20150159. Epub 2015 Apr 8. Biochem J. 2015. PMID: 25851527

5

Copper Binding and Subsequent Aggregation of α-Synuclein Are Modulated by N-Terminal Acetylation and Ablated by the H50Q Missense Mutation.

Mason RJ, Paskins AR, Dalton CF, Smith DP. Mason RJ, et al. Among authors: smith dp. Biochemistry. 2016 Aug 30;55(34):4737-41. doi: 10.1021/acs.biochem.6b00708. Epub 2016 Aug 18. Biochemistry. 2016. PMID: 27517125

6

Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson's disease.

Duce JA, Wong BX, Durham H, Devedjian JC, Smith DP, Devos D. Duce JA, et al. Among authors: smith dp. Mol Neurodegener. 2017 Jun 7;12(1):45. doi: 10.1186/s13024-017-0186-8. Mol Neurodegener. 2017. PMID: 28592304 Free PMC article. Review.

7

Mass spectrometry imaging of endogenous metabolites in response to doxorubicin in a novel 3D osteosarcoma cell culture model.

Palubeckaitė I, Crooks L, Smith DP, Cole LM, Bram H, Le Maitre C, Clench MR, Cross NA. Palubeckaitė I, et al. Among authors: smith dp. J Mass Spectrom. 2020 Apr;55(4):e4461. doi: 10.1002/jms.4461. Epub 2019 Dec 2. J Mass Spectrom. 2020. PMID: 31654532

8

The N-terminal residues 43 to 60 form the interface for dopamine mediated α-synuclein dimerisation.

Leong SL, Hinds MG, Connor AR, Smith DP, Illes-Toth E, Pham CL, Barnham KJ, Cappai R. Leong SL, et al. Among authors: smith dp. PLoS One. 2015 Feb 13;10(2):e0116497. doi: 10.1371/journal.pone.0116497. eCollection 2015. PLoS One. 2015. PMID: 25679387 Free PMC article.

9

Characterization of an Aggregated Three-Dimensional Cell Culture Model by Multimodal Mass Spectrometry Imaging.

Flint LE, Hamm G, Ready JD, Ling S, Duckett CJ, Cross NA, Cole LM, Smith DP, Goodwin RJA, Clench MR. Flint LE, et al. Among authors: smith dp. Anal Chem. 2020 Sep 15;92(18):12538-12547. doi: 10.1021/acs.analchem.0c02389. Epub 2020 Aug 14. Anal Chem. 2020. PMID: 32786495 Free PMC article.

10

Comparative Analysis of the Relative Fragmentation Stabilities of Polymorphic Alpha-Synuclein Amyloid Fibrils.

Sanami S, Purton TJ, Smith DP, Tuite MF, Xue WF. Sanami S, et al. Among authors: smith dp. Biomolecules. 2022 Apr 25;12(5):630. doi: 10.3390/biom12050630. Biomolecules. 2022. PMID: 35625557 Free PMC article.

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