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Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis.
Heun Y, Pircher J, Czermak T, Bluem P, Hupel G, Bohmer M, Kraemer BF, Pogoda K, Pfeifer A, Woernle M, Ribeiro A, Hübner M, Kreth S, Claus RA, Weis S, Ungelenk L, Krötz F, Pohl U, Mannell H. Heun Y, et al. Among authors: weis s. EBioMedicine. 2019 Apr;42:120-132. doi: 10.1016/j.ebiom.2019.03.034. Epub 2019 Mar 21. EBioMedicine. 2019. PMID: 30905847 Free PMC article.
Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis.
Rademann P, Weidinger A, Drechsler S, Meszaros A, Zipperle J, Jafarmadar M, Dumitrescu S, Hacobian A, Ungelenk L, Röstel F, Kaszaki J, Szabo A, Skulachev VP, Bauer M, Bahrami S, Weis S, Kozlov AV, Osuchowski MF. Rademann P, et al. Among authors: weis s. Oxid Med Cell Longev. 2017;2017:6412682. doi: 10.1155/2017/6412682. Epub 2017 Sep 19. Oxid Med Cell Longev. 2017. PMID: 29104729 Free PMC article.
Bridging animal and clinical research during SARS-CoV-2 pandemic: A new-old challenge.
Winkler MS, Skirecki T, Brunkhorst FM, Cajander S, Cavaillon JM, Ferrer R, Flohé SB, García-Salido A, Giamarellos-Bourboulis EJ, Girardis M, Kox M, Lachmann G, Martin-Loeches I, Netea MG, Spinetti T, Schefold JC, Torres A, Uhle F, Venet F, Weis S, Scherag A, Rubio I, Osuchowski MF. Winkler MS, et al. Among authors: weis s. EBioMedicine. 2021 Apr;66:103291. doi: 10.1016/j.ebiom.2021.103291. Epub 2021 Apr 1. EBioMedicine. 2021. PMID: 33813139 Free PMC article. Review.
Labile heme impairs hepatic microcirculation and promotes hepatic injury.
Englert FA, Seidel RA, Galler K, Gouveia Z, Soares MP, Neugebauer U, Clemens MG, Sponholz C, Heinemann SH, Pohnert G, Bauer M, Weis S. Englert FA, et al. Among authors: weis s. Arch Biochem Biophys. 2019 Sep 15;672:108075. doi: 10.1016/j.abb.2019.108075. Epub 2019 Aug 11. Arch Biochem Biophys. 2019. PMID: 31412260
Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis.
Vandewalle J, Timmermans S, Paakinaho V, Vancraeynest L, Dewyse L, Vanderhaeghen T, Wallaeys C, Van Wyngene L, Van Looveren K, Nuyttens L, Eggermont M, Dewaele S, Velho TR, Moita LF, Weis S, Sponholz C, van Grunsven LA, Dewerchin M, Carmeliet P, De Bosscher K, Van de Voorde J, Palvimo JJ, Libert C. Vandewalle J, et al. Among authors: weis s. Cell Metab. 2021 Sep 7;33(9):1763-1776.e5. doi: 10.1016/j.cmet.2021.07.002. Epub 2021 Jul 23. Cell Metab. 2021. PMID: 34302744 Free article.
Tidy up - The unfolded protein response in sepsis.
Vivas W, Weis S. Vivas W, et al. Among authors: weis s. Front Immunol. 2022 Oct 20;13:980680. doi: 10.3389/fimmu.2022.980680. eCollection 2022. Front Immunol. 2022. PMID: 36341413 Free PMC article. Review.
Metabolic Adaptation Establishes Disease Tolerance to Sepsis.
Weis S, Carlos AR, Moita MR, Singh S, Blankenhaus B, Cardoso S, Larsen R, Rebelo S, Schäuble S, Del Barrio L, Mithieux G, Rajas F, Lindig S, Bauer M, Soares MP. Weis S, et al. Cell. 2017 Jun 15;169(7):1263-1275.e14. doi: 10.1016/j.cell.2017.05.031. Cell. 2017. PMID: 28622511 Free PMC article.
Host cystathionine-γ lyase derived hydrogen sulfide protects against Pseudomonas aeruginosa sepsis.
Renieris G, Droggiti DE, Katrini K, Koufargyris P, Gkavogianni T, Karakike E, Antonakos N, Damoraki G, Karageorgos A, Sabracos L, Katsouda A, Jentho E, Weis S, Wang R, Bauer M, Szabo C, Platoni K, Kouloulias V, Papapetropoulos A, Giamarellos-Bourboulis EJ. Renieris G, et al. Among authors: weis s. PLoS Pathog. 2021 Mar 26;17(3):e1009473. doi: 10.1371/journal.ppat.1009473. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33770141 Free PMC article.
637 results