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Plasmodium falciparum glycogen synthase kinase-3: molecular model, expression, intracellular localisation and selective inhibitors.
Droucheau E, Primot A, Thomas V, Mattei D, Knockaert M, Richardson C, Sallicandro P, Alano P, Jafarshad A, Baratte B, Kunick C, Parzy D, Pearl L, Doerig C, Meijer L. Droucheau E, et al. Among authors: kunick c. Biochim Biophys Acta. 2004 Mar 11;1697(1-2):181-96. doi: 10.1016/j.bbapap.2003.11.023. Biochim Biophys Acta. 2004. PMID: 15023360 Review.
Identification of 2-anilino-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-ones as dual PLK1/VEGF-R2 kinase inhibitor chemotypes by structure-based lead generation.
Egert-Schmidt AM, Dreher J, Dunkel U, Kohfeld S, Preu L, Weber H, Ehlert JE, Mutschler B, Totzke F, Schächtele C, Kubbutat MH, Baumann K, Kunick C. Egert-Schmidt AM, et al. Among authors: kunick c. J Med Chem. 2010 Mar 25;53(6):2433-42. doi: 10.1021/jm901388c. J Med Chem. 2010. PMID: 20170163
3,6-Diamino-4-(2-halophenyl)-2-benzoylthieno[2,3-b]pyridine-5-carbonitriles are selective inhibitors of Plasmodium falciparum glycogen synthase kinase-3.
Fugel W, Oberholzer AE, Gschloessl B, Dzikowski R, Pressburger N, Preu L, Pearl LH, Baratte B, Ratin M, Okun I, Doerig C, Kruggel S, Lemcke T, Meijer L, Kunick C. Fugel W, et al. Among authors: kunick c. J Med Chem. 2013 Jan 10;56(1):264-75. doi: 10.1021/jm301575n. Epub 2012 Dec 27. J Med Chem. 2013. PMID: 23214499
2-Arylpaullones are selective antitrypanosomal agents.
Ryczak J, Papini M, Lader A, Nasereddin A, Kopelyanskiy D, Preu L, Jaffe CL, Kunick C. Ryczak J, et al. Among authors: kunick c. Eur J Med Chem. 2013 Jun;64:396-400. doi: 10.1016/j.ejmech.2013.03.065. Epub 2013 Apr 10. Eur J Med Chem. 2013. PMID: 23648975
76 results