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LC-MS/MS method for determination of cyclin-dependent kinase inhibitors, BP-14 and BP-20, and its application in pharmacokinetic study in rat.
Široká J, Čečková M, Urbánek L, Kryštof V, Gucký T, Hofman J, Strnad M, Štaud F. Široká J, et al. Among authors: gucky t. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jul 1;1089:24-32. doi: 10.1016/j.jchromb.2018.04.049. Epub 2018 May 1. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 29753211
Discovery of N2-(4-Amino-cyclohexyl)-9-cyclopentyl- N6-(4-morpholin-4-ylmethyl-phenyl)- 9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 Mutations.
Gucký T, Řezníčková E, Radošová Muchová T, Jorda R, Klejová Z, Malínková V, Berka K, Bazgier V, Ajani H, Lepšík M, Divoký V, Kryštof V. Gucký T, et al. J Med Chem. 2018 May 10;61(9):3855-3869. doi: 10.1021/acs.jmedchem.7b01529. Epub 2018 Apr 30. J Med Chem. 2018. PMID: 29672049
6-Substituted purines as ROCK inhibitors with anti-metastatic activity.
Voller J, Zahajská L, Plíhalová L, Jeřábková J, Burget D, Pataki AC, Kryštof V, Zatloukal M, Brábek J, Rösel D, Mik V, Tkáč M, Pospíšil T, Gucký T, Doležal K, Strnad M. Voller J, et al. Among authors: gucky t. Bioorg Chem. 2019 Sep;90:103005. doi: 10.1016/j.bioorg.2019.103005. Epub 2019 Jun 6. Bioorg Chem. 2019. PMID: 31271944
28 results