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Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7015-7020. doi: 10.1073/pnas.1814685116. Epub 2019 Mar 20.
Proc Natl Acad Sci U S A. 2019.
PMID: 30894487
Free PMC article.
Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis.
Ojo KK, Ranade RM, Zhang Z, Dranow DM, Myers JB, Choi R, Nakazawa Hewitt S, Edwards TE, Davies DR, Lorimer D, Boyle SM, Barrett LK, Buckner FS, Fan E, Van Voorhis WC.
Ojo KK, et al. Among authors: nakazawa hewitt s.
PLoS One. 2016 Aug 8;11(8):e0160350. doi: 10.1371/journal.pone.0160350. eCollection 2016.
PLoS One. 2016.
PMID: 27500735
Free PMC article.
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Structures of a histidine triad family protein from Entamoeba histolytica bound to sulfate, AMP and GMP.
Lorimer DD, Choi R, Abramov A, Nakazawa Hewitt S, Gardberg AS, Van Voorhis WC, Staker BL, Myler PJ, Edwards TE.
Lorimer DD, et al. Among authors: nakazawa hewitt s.
Acta Crystallogr F Struct Biol Commun. 2015 May;71(Pt 5):572-6. doi: 10.1107/S2053230X1500237X. Epub 2015 Apr 21.
Acta Crystallogr F Struct Biol Commun. 2015.
PMID: 25945711
Free PMC article.
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Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP.
Moen SO, Fairman JW, Barnes SR, Sullivan A, Nakazawa-Hewitt S, Van Voorhis WC, Staker BL, Lorimer DD, Myler PJ, Edwards TE.
Moen SO, et al. Among authors: nakazawa hewitt s.
Acta Crystallogr F Struct Biol Commun. 2015 May;71(Pt 5):609-14. doi: 10.1107/S2053230X15006883. Epub 2015 Apr 21.
Acta Crystallogr F Struct Biol Commun. 2015.
PMID: 25945716
Free PMC article.
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Correction: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis.
Ojo KK, Ranade RM, Zhang Z, Dranow DM, Myers JB, Choi R, Nakazawa Hewitt S, Edwards TE, Davies DR, Lorimer D, Boyle SM, Barrett LK, Buckner FS, Fan E, Van Voorhis WC.
Ojo KK, et al. Among authors: nakazawa hewitt s.
PLoS One. 2016 Sep 22;11(9):e0163641. doi: 10.1371/journal.pone.0163641. eCollection 2016.
PLoS One. 2016.
PMID: 27658298
Free PMC article.
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Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV, Avery VM, Ayong L, Baker M, Baker S, Ben Mamoun C, Bhatia S, Bickle Q, Bounaadja L, Bowling T, Bosch J, Boucher LE, Boyom FF, Brea J, Brennan M, Burton A, Caffrey CR, Camarda G, Carrasquilla M, Carter D, Belen Cassera M, Chih-Chien Cheng K, Chindaudomsate W, Chubb A, Colon BL, Colón-López DD, Corbett Y, Crowther GJ, Cowan N, D'Alessandro S, Le Dang N, Delves M, DeRisi JL, Du AY, Duffy S, Abd El-Salam El-Sayed S, Ferdig MT, Fernández Robledo JA, Fidock DA, Florent I, Fokou PV, Galstian A, Gamo FJ, Gokool S, Gold B, Golub T, Goldgof GM, Guha R, Guiguemde WA, Gural N, Guy RK, Hansen MA, Hanson KK, Hemphill A, Hooft van Huijsduijnen R, Horii T, Horrocks P, Hughes TB, Huston C, Igarashi I, Ingram-Sieber K, Itoe MA, Jadhav A, Naranuntarat Jensen A, Jensen LT, Jiang RH, Kaiser A, Keiser J, Ketas T, Kicka S, Kim S, Kirk K, Kumar VP, Kyle DE, Lafuente MJ, Landfear S, Lee N, Lee S, Lehane AM, Li F, Little D, Liu L, Llinás M, Loza MI, Lubar A, Lucantoni L, Lucet I, Maes L, Mancama D, Mansour NR, March S, McGowan S, Medina Vera I, Meister S, Mercer L, Mestr…
See abstract for full author list ➔
Van Voorhis WC, et al. Among authors: nakazawa hewitt s.
PLoS Pathog. 2016 Jul 28;12(7):e1005763. doi: 10.1371/journal.ppat.1005763. eCollection 2016 Jul.
PLoS Pathog. 2016.
PMID: 27467575
Free PMC article.
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Combining functional and structural genomics to sample the essential Burkholderia structome.
Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D 3rd, Staker BL, Phan I, Gillespie A, Choi R, Nakazawa-Hewitt S, Nguyen MT, Napuli A, Barrett L, Buchko GW, Stacy R, Myler PJ, Stewart LJ, Manoil C, Van Voorhis WC.
Baugh L, et al. Among authors: nakazawa hewitt s.
PLoS One. 2013;8(1):e53851. doi: 10.1371/journal.pone.0053851. Epub 2013 Jan 31.
PLoS One. 2013.
PMID: 23382856
Free PMC article.
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Prediction of protein crystallization outcome using a hybrid method.
Zucker FH, Stewart C, dela Rosa J, Kim J, Zhang L, Xiao L, Ross J, Napuli AJ, Mueller N, Castaneda LJ, Nakazawa Hewitt SR, Arakaki TL, Larson ET, Subramanian E, Verlinde CL, Fan E, Buckner FS, Van Voorhis WC, Merritt EA, Hol WG.
Zucker FH, et al. Among authors: nakazawa hewitt sr.
J Struct Biol. 2010 Jul;171(1):64-73. doi: 10.1016/j.jsb.2010.03.016. Epub 2010 Mar 27.
J Struct Biol. 2010.
PMID: 20347992
Free PMC article.
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