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Modeling Patient-Derived Glioblastoma with Cerebral Organoids.
Linkous A, Balamatsias D, Snuderl M, Edwards L, Miyaguchi K, Milner T, Reich B, Cohen-Gould L, Storaska A, Nakayama Y, Schenkein E, Singhania R, Cirigliano S, Magdeldin T, Lin Y, Nanjangud G, Chadalavada K, Pisapia D, Liston C, Fine HA. Linkous A, et al. Among authors: cirigliano s. Cell Rep. 2019 Mar 19;26(12):3203-3211.e5. doi: 10.1016/j.celrep.2019.02.063. Cell Rep. 2019. PMID: 30893594 Free PMC article.
Tumor Microenvironment Is Critical for the Maintenance of Cellular States Found in Primary Glioblastomas.
Pine AR, Cirigliano SM, Nicholson JG, Hu Y, Linkous A, Miyaguchi K, Edwards L, Singhania R, Schwartz TH, Ramakrishna R, Pisapia DJ, Snuderl M, Elemento O, Fine HA. Pine AR, et al. Among authors: cirigliano sm. Cancer Discov. 2020 Jul;10(7):964-979. doi: 10.1158/2159-8290.CD-20-0057. Epub 2020 Apr 6. Cancer Discov. 2020. PMID: 32253265 Free PMC article.
All-trans retinoic acid and protein kinase C α/β1 inhibitor combined treatment targets cancer stem cells and impairs breast tumor progression.
Berardi DE, Ariza Bareño L, Amigo N, Cañonero L, Pelagatti MLN, Motter AN, Taruselli MA, Díaz Bessone MI, Cirigliano SM, Edelstein A, Peters MG, Diament M, Urtreger AJ, Todaro LB. Berardi DE, et al. Among authors: cirigliano sm. Sci Rep. 2021 Mar 15;11(1):6044. doi: 10.1038/s41598-021-85344-w. Sci Rep. 2021. PMID: 33723318 Free PMC article.
Protein Kinase C Alpha (PKCα) overexpression leads to a better response to retinoid acid therapy through Retinoic Acid Receptor Beta (RARβ) activation in mammary cancer cells.
Bessone MID, Berardi DE, Cirigliano SM, Delbart DI, Peters MG, Todaro LB, Urtreger AJ. Bessone MID, et al. Among authors: cirigliano sm. J Cancer Res Clin Oncol. 2020 Dec;146(12):3241-3253. doi: 10.1007/s00432-020-03368-7. Epub 2020 Aug 31. J Cancer Res Clin Oncol. 2020. PMID: 32865619