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Structure-Activity Relationship Studies of 3- or 4-Pyridine Derivatives of DS-6930.
Shinozuka T, Tsukada T, Fujii K, Tokumaru E, Matsui Y, Wakimoto S, Ogata T, Araki K, Sawamura R, Watanabe N, Mori M, Tanaka J. Shinozuka T, et al. Among authors: matsui y. ACS Med Chem Lett. 2019 Feb 26;10(3):358-362. doi: 10.1021/acsmedchemlett.8b00645. eCollection 2019 Mar 14. ACS Med Chem Lett. 2019. PMID: 30891140 Free PMC article.
Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor.
Nakamura Y, Fujimoto T, Ogawa Y, Sugita C, Miyazaki S, Tamaki K, Takahashi M, Matsui Y, Nagayama T, Manabe K, Mizuno M, Masubuchi N, Chiba K, Nishi T. Nakamura Y, et al. Among authors: matsui y. ACS Med Chem Lett. 2012 Aug 18;3(9):754-8. doi: 10.1021/ml300168e. eCollection 2012 Sep 13. ACS Med Chem Lett. 2012. PMID: 24900544 Free PMC article.
Discovery of DS-6930, a potent selective PPARγ modulator. Part II: Lead optimization.
Shinozuka T, Tsukada T, Fujii K, Tokumaru E, Shimada K, Onishi Y, Matsui Y, Wakimoto S, Kuroha M, Ogata T, Araki K, Ohsumi J, Sawamura R, Watanabe N, Yamamoto H, Fujimoto K, Tani Y, Mori M, Tanaka J. Shinozuka T, et al. Among authors: matsui y. Bioorg Med Chem. 2018 Oct 1;26(18):5099-5117. doi: 10.1016/j.bmc.2018.09.005. Epub 2018 Sep 8. Bioorg Med Chem. 2018. PMID: 30220602
Discovery of DS-6930, a potent selective PPARγ modulator. Part I: Lead identification.
Shinozuka T, Tsukada T, Fujii K, Tokumaru E, Shimada K, Onishi Y, Matsui Y, Wakimoto S, Kuroha M, Ogata T, Araki K, Ohsumi J, Sawamura R, Watanabe N, Yamamoto H, Fujimoto K, Tani Y, Mori M, Tanaka J. Shinozuka T, et al. Among authors: matsui y. Bioorg Med Chem. 2018 Oct 1;26(18):5079-5098. doi: 10.1016/j.bmc.2018.09.006. Epub 2018 Sep 8. Bioorg Med Chem. 2018. PMID: 30241907
Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold.
Kawai J, Ota M, Ohki H, Toki T, Suzuki M, Shimada T, Matsui S, Inoue H, Sugihara C, Matsuhashi N, Matsui Y, Takaishi S, Nakayama K. Kawai J, et al. Among authors: matsui s, matsui y. ACS Med Chem Lett. 2019 May 24;10(6):893-898. doi: 10.1021/acsmedchemlett.9b00069. eCollection 2019 Jun 13. ACS Med Chem Lett. 2019. PMID: 31223444 Free PMC article.
2,553 results