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Macitentan inhibits the transforming growth factor-β profibrotic action, blocking the signaling mediated by the ETR/TβRI complex in systemic sclerosis dermal fibroblasts.
Cipriani P, Di Benedetto P, Ruscitti P, Verzella D, Fischietti M, Zazzeroni F, Liakouli V, Carubbi F, Berardicurti O, Alesse E, Giacomelli R. Cipriani P, et al. Among authors: di benedetto p. Arthritis Res Ther. 2015 Sep 10;17(1):247. doi: 10.1186/s13075-015-0754-7. Arthritis Res Ther. 2015. PMID: 26357964 Free PMC article.
Mesenchymal stem cells of Systemic Sclerosis patients, derived from different sources, show a profibrotic microRNA profiling.
Di Benedetto P, Panzera N, Cipriani P, Mastroiaco V, Tessitore A, Liakouli V, Ruscitti P, Berardicurti O, Carubbi F, Guggino G, Bianchi A, Di Marco A, Ciccia F, Alesse E, Giacomelli R. Di Benedetto P, et al. Among authors: di marco a. Sci Rep. 2019 May 9;9(1):7144. doi: 10.1038/s41598-019-43638-0. Sci Rep. 2019. PMID: 31073190 Free PMC article.
Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1β via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3(NLRP3)-inflammasome activation: a possible implication for therapeutic decision in these patients.
Ruscitti P, Cipriani P, Di Benedetto P, Liakouli V, Berardicurti O, Carubbi F, Ciccia F, Alvaro S, Triolo G, Giacomelli R. Ruscitti P, et al. Among authors: di benedetto p. Clin Exp Immunol. 2015 Oct;182(1):35-44. doi: 10.1111/cei.12667. Epub 2015 Jul 19. Clin Exp Immunol. 2015. PMID: 26095630 Free PMC article.
H-ferritin and CD68(+) /H-ferritin(+) monocytes/macrophages are increased in the skin of adult-onset Still's disease patients and correlate with the multi-visceral involvement of the disease.
Ruscitti P, Cipriani P, Ciccia F, Di Benedetto P, Liakouli V, Berardicurti O, Carubbi F, Guggino G, Di Bartolomeo S, Triolo G, Giacomelli R. Ruscitti P, et al. Among authors: di benedetto p, di bartolomeo s. Clin Exp Immunol. 2016 Oct;186(1):30-8. doi: 10.1111/cei.12826. Epub 2016 Jul 28. Clin Exp Immunol. 2016. PMID: 27317930 Free PMC article.
185 results