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Increased ROS generation causes apoptosis-like death: Mechanistic insights into the anti-Leishmania activity of a potent ruthenium(II) complex.
Costa MS, Gonçalves YG, Teixeira SC, Nunes DCO, Lopes DS, da Silva CV, da Silva MS, Borges BC, Silva MJB, Rodrigues RS, Rodrigues VM, Von Poelhsitz G, Yoneyama KAG. Costa MS, et al. Among authors: von poelhsitz g. J Inorg Biochem. 2019 Jun;195:1-12. doi: 10.1016/j.jinorgbio.2019.03.005. Epub 2019 Mar 6. J Inorg Biochem. 2019. PMID: 30861423
Synthesis, characterization, X-ray structure and in vitro antimycobacterial and antitumoral activities of Ru(II) phosphine/diimine complexes containing the "SpymMe2" ligand, SpymMe2=4,6-dimethyl-2-mercaptopyrimidine.
do Nascimento FB, Von Poelhsitz G, Pavan FR, Sato DN, Leite CQ, Selistre-de-Araújo HS, Ellena J, Castellano EE, Deflon VM, Batista AA. do Nascimento FB, et al. Among authors: von poelhsitz g. J Inorg Biochem. 2008 Sep;102(9):1783-9. doi: 10.1016/j.jinorgbio.2008.05.009. Epub 2008 May 29. J Inorg Biochem. 2008. PMID: 18614238
Ruthenium(II) complexes of 1,3-thiazolidine-2-thione: Cytotoxicity against tumor cells and anti-Trypanosoma cruzi activity enhanced upon combination with benznidazole.
Corrêa RS, da Silva MM, Graminha AE, Meira CS, Santos JA, Moreira DR, Soares MB, Von Poelhsitz G, Castellano EE, Bloch C Jr, Cominetti MR, Batista AA. Corrêa RS, et al. Among authors: von poelhsitz g. J Inorg Biochem. 2016 Mar;156:153-63. doi: 10.1016/j.jinorgbio.2015.12.024. Epub 2016 Jan 2. J Inorg Biochem. 2016. PMID: 26795676
Ruthenium (II) complex cis-[RuII(ŋ2-O2CC7H7O2)(dppm)2]PF6-hmxbato induces ROS-mediated apoptosis in lung tumor cells producing selective cytotoxicity.
Costa MS, Gonçalves YG, Borges BC, Silva MJB, Amstalden MK, Costa TR, Antunes LMG, Rodrigues RS, Rodrigues VM, de Faria Franca E, Zoia MAP, de Araújo TG, Goulart LR, Von Poelhsitz G, Yoneyama KAG. Costa MS, et al. Among authors: von poelhsitz g. Sci Rep. 2020 Sep 21;10(1):15410. doi: 10.1038/s41598-020-72420-w. Sci Rep. 2020. PMID: 32958783 Free PMC article.
Organometallic Complex Strongly Impairs Chikungunya Virus Entry to the Host Cells.
de Oliveira DM, Santos IA, Martins DOS, Gonçalves YG, Cardoso-Sousa L, Sabino-Silva R, Von Poelhsitz G, Franca EF, Nicolau-Junior N, Pacca CC, Merits A, Harris M, Jardim ACG. de Oliveira DM, et al. Among authors: von poelhsitz g. Front Microbiol. 2020 Dec 15;11:608924. doi: 10.3389/fmicb.2020.608924. eCollection 2020. Front Microbiol. 2020. PMID: 33384677 Free PMC article.
New ruthenium(II) complexes with cyclic thio- and semicarbazone: evaluation of cytotoxicity and effects on cell migration and apoptosis of lung cancer cells.
Gonçalves YG, Becceneri AB, Graminha AE, Miranda VM, Rios RR, Rinaldi-Neto F, Costa MS, Gonçalves ACR, Deflon VM, Yoneyama KAG, Maia PIS, Franca EF, Cominetti MR, Silva RS, Von Poelhsitz G. Gonçalves YG, et al. Among authors: von poelhsitz g. Dalton Trans. 2023 Jul 18;52(28):9590-9606. doi: 10.1039/d3dt00750b. Dalton Trans. 2023. PMID: 37377063
15 results