Leandrou E - Search Results

1

Vitamin B₁₂ modulates Parkinson's disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection.

Schaffner A, Li X, Gomez-Llorente Y, Leandrou E, Memou A, Clemente N, Yao C, Afsari F, Zhi L, Pan N, Morohashi K, Hua X, Zhou MM, Wang C, Zhang H, Chen SG, Elliott CJ, Rideout H, Ubarretxena-Belandia I, Yue Z. Schaffner A, et al. Among authors: leandrou e. Cell Res. 2019 Apr;29(4):313-329. doi: 10.1038/s41422-019-0153-8. Epub 2019 Mar 11. Cell Res. 2019. PMID: 30858560 Free PMC article.

2

Kinase activity of mutant LRRK2 manifests differently in hetero-dimeric vs. homo-dimeric complexes.

Leandrou E, Markidi E, Memou A, Melachroinou K, Greggio E, Rideout HJ. Leandrou E, et al. Biochem J. 2019 Feb 8;476(3):559-579. doi: 10.1042/BCJ20180589. Biochem J. 2019. PMID: 30670570

3

Activation of FADD-Dependent Neuronal Death Pathways as a Predictor of Pathogenicity for LRRK2 Mutations.

Melachroinou K, Leandrou E, Valkimadi PE, Memou A, Hadjigeorgiou G, Stefanis L, Rideout HJ. Melachroinou K, et al. Among authors: leandrou e. PLoS One. 2016 Nov 10;11(11):e0166053. doi: 10.1371/journal.pone.0166053. eCollection 2016. PLoS One. 2016. PMID: 27832104 Free PMC article.

4

A motif within the armadillo repeat of Parkinson's-linked LRRK2 interacts with FADD to hijack the extrinsic death pathway.

Antoniou N, Vlachakis D, Memou A, Leandrou E, Valkimadi PE, Melachroinou K, Re DB, Przedborski S, Dauer WT, Stefanis L, Rideout HJ. Antoniou N, et al. Among authors: leandrou e. Sci Rep. 2018 Feb 22;8(1):3455. doi: 10.1038/s41598-018-21931-8. Sci Rep. 2018. PMID: 29472595 Free PMC article.

5

Voltage-Gated Calcium Channels and α-Synuclein: Implications in Parkinson's Disease.

Leandrou E, Emmanouilidou E, Vekrellis K. Leandrou E, et al. Front Mol Neurosci. 2019 Oct 9;12:237. doi: 10.3389/fnmol.2019.00237. eCollection 2019. Front Mol Neurosci. 2019. PMID: 31649506 Free PMC article. Review.

6

Elevated Serum α-Synuclein Levels in Huntington's Disease Patients.

Breza M, Emmanouilidou E, Leandrou E, Kartanou C, Bougea A, Panas M, Stefanis L, Karadima G, Vekrellis K, Koutsis G. Breza M, et al. Among authors: leandrou e. Neuroscience. 2020 Apr 1;431:34-39. doi: 10.1016/j.neuroscience.2020.01.037. Epub 2020 Feb 8. Neuroscience. 2020. PMID: 32045629

7

Intrastriatal Administration of Exosome-Associated Pathological Alpha-Synuclein Is Not Sufficient by Itself to Cause Pathology Transmission.

Karampetsou M, Sykioti VS, Leandrou E, Melachroinou K, Lambiris A, Giannelos A, Emmanouilidou E, Vekrellis K. Karampetsou M, et al. Among authors: leandrou e. Front Neurosci. 2020 Apr 21;14:246. doi: 10.3389/fnins.2020.00246. eCollection 2020. Front Neurosci. 2020. PMID: 32372894 Free PMC article.

8

α-Synuclein oligomers potentiate neuroinflammatory NF-κB activity and induce Ca_v3.2 calcium signaling in astrocytes.

Leandrou E, Chalatsa I, Anagnostou D, Machalia C, Semitekolou M, Filippa V, Makridakis M, Vlahou A, Anastasiadou E, Vekrellis K, Emmanouilidou E. Leandrou E, et al. Transl Neurodegener. 2024 Feb 21;13(1):11. doi: 10.1186/s40035-024-00401-4. Transl Neurodegener. 2024. PMID: 38378800 Free PMC article.

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