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Page 1
Oral administration of carvacrol/β-cyclodextrin complex protects against 6-hydroxydopamine-induced dopaminergic denervation.
Tiefensee Ribeiro C, Gasparotto J, Petiz LL, Brum PO, Peixoto DO, Kunzler A, da Rosa Silva HT, Bortolin RC, Almeida RF, Quintans-Junior LJ, Araújo AA, Moreira JCF, Gelain DP. Tiefensee Ribeiro C, et al. Among authors: brum po. Neurochem Int. 2019 Jun;126:27-35. doi: 10.1016/j.neuint.2019.02.021. Epub 2019 Mar 5. Neurochem Int. 2019. PMID: 30849398 Free article.
Extracellular HSP70 Activates ERK1/2, NF-kB and Pro-Inflammatory Gene Transcription Through Binding with RAGE in A549 Human Lung Cancer Cells.
Somensi N, Brum PO, de Miranda Ramos V, Gasparotto J, Zanotto-Filho A, Rostirolla DC, da Silva Morrone M, Moreira JCF, Pens Gelain D. Somensi N, et al. Among authors: brum po. Cell Physiol Biochem. 2017;42(6):2507-2522. doi: 10.1159/000480213. Epub 2017 Aug 22. Cell Physiol Biochem. 2017. PMID: 28848092 Free article.
Nuclear RXRα and RXRβ receptors exert distinct and opposite effects on RA-mediated neuroblastoma differentiation.
Girardi CS, Rostirolla DC, Lini FJM, Brum PO, Delgado J, Ribeiro CT, Teixeira AA, Peixoto DO, Heimfarth L, Kunzler A, Moreira JCF, Gelain DP. Girardi CS, et al. Among authors: brum po. Biochim Biophys Acta Mol Cell Res. 2019 Mar;1866(3):317-328. doi: 10.1016/j.bbamcr.2018.11.014. Epub 2018 Dec 7. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30529222 Free article.
High fat diet-induced obesity causes a reduction in brain tyrosine hydroxylase levels and non-motor features in rats through metabolic dysfunction, neuroinflammation and oxidative stress.
Bittencourt A, Brum PO, Ribeiro CT, Gasparotto J, Bortolin RC, de Vargas AR, Heimfarth L, de Almeida RF, Moreira JCF, de Oliveira J, Gelain DP. Bittencourt A, et al. Among authors: brum po. Nutr Neurosci. 2022 May;25(5):1026-1040. doi: 10.1080/1028415X.2020.1831261. Epub 2020 Oct 20. Nutr Neurosci. 2022. PMID: 33078695
Neurological impairment caused by Schistosoma mansoni systemic infection exhibits early features of idiopathic neurodegenerative disease.
Gasparotto J, Senger MR, Telles de Sá Moreira E, Brum PO, Carazza Kessler FG, Peixoto DO, Panzenhagen AC, Ong LK, Campos Soares M, Reis PA, Schirato GV, Góes Valente WC, Araújo Montoya BO, Silva FP, Fonseca Moreira JC, Dal-Pizzol F, Castro-Faria-Neto HC, Gelain DP. Gasparotto J, et al. Among authors: brum po. J Biol Chem. 2021 Aug;297(2):100979. doi: 10.1016/j.jbc.2021.100979. Epub 2021 Jul 22. J Biol Chem. 2021. PMID: 34303703 Free PMC article.
Hypoxia-Inducible Factor-1α (HIF-1α) Inhibition Impairs Retinoic Acid-Induced Differentiation in SH-SY5Y Neuroblastoma Cells, Leading to Reduced Neurite Length and Diminished Gene Expression Related to Cell Differentiation.
Brum PO, Viola GD, Saibro-Girardi C, Tiefensee-Ribeiro C, Brum MO, Gasparotto J, Krolow R, Moreira JCF, Gelain DP. Brum PO, et al. Neurochem Res. 2022 Feb;47(2):409-421. doi: 10.1007/s11064-021-03454-3. Epub 2021 Sep 23. Neurochem Res. 2022. PMID: 34557995 Free PMC article.
Intranasal HSP70 administration protects against dopaminergic denervation and modulates neuroinflammatory response in the 6-OHDA rat model.
Tiefensee Ribeiro C, Peixoto DO, Santos L, Saibro-Girardi C, Brum PO, Carazza-Kessler FG, Somensi N, Behrens LMP, Bittencourt RR, Soares LS, Silveira AK, de Oliveira J, Moreira JCF, Gasparotto J, Gelain DP. Tiefensee Ribeiro C, et al. Among authors: brum po. Brain Behav Immun Health. 2021 Mar 31;14:100253. doi: 10.1016/j.bbih.2021.100253. eCollection 2021 Jul. Brain Behav Immun Health. 2021. PMID: 34589762 Free PMC article.
Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress.
Mautone Gomes H, Silveira AK, Gasparotto J, Bortolin RC, Terra SR, Brum PO, Gelain DP, Fonseca Moreira JC. Mautone Gomes H, et al. Among authors: brum po. J Nutr Biochem. 2023 Apr;114:109272. doi: 10.1016/j.jnutbio.2023.109272. Epub 2023 Jan 18. J Nutr Biochem. 2023. PMID: 36681309
Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE).
Peixoto DO, Bittencourt RR, Gasparotto J, Kessler FGC, Brum PO, Somensi N, Girardi CS, Dos Santos da Silva L, Outeiro TF, Moreira JCF, Gelain DP. Peixoto DO, et al. Among authors: brum po. J Neurochem. 2023 Sep 3. doi: 10.1111/jnc.15956. Online ahead of print. J Neurochem. 2023. PMID: 37661637
Histone 3 Trimethylation Patterns are Associated with Resilience or Stress Susceptibility in a Rat Model of Major Depression Disorder.
Santos L, Behrens L, Barbosa C, Tiefensee-Ribeiro C, Rosa-Silva H, Somensi N, Brum PO, Silveira AK, Rodrigues MS, de Oliveira J, Gelain DP, Almeida RF, Moreira JCF. Santos L, et al. Among authors: brum po. Mol Neurobiol. 2024 Jan 16. doi: 10.1007/s12035-024-03912-3. Online ahead of print. Mol Neurobiol. 2024. PMID: 38225513
11 results