Pizarro JC - Search Results

1

Disruption of the Putative Ribosome-Binding Motif of a Scaffold Protein Impairs Cytochrome c Oxidase Subunit Expression in Leishmania major.

Cardenas D, Sylvester C, Cao B, Nation CS, Pizarro JC, Lu H, Guidry J, Wojcik EJ, Kelly BL. Cardenas D, et al. Among authors: pizarro jc. mSphere. 2019 Mar 6;4(2):e00644-18. doi: 10.1128/mSphere.00644-18. mSphere. 2019. PMID: 30842271 Free PMC article.

2

LACK, a RACK1 ortholog, facilitates cytochrome c oxidase subunit expression to promote Leishmania major fitness.

Cardenas D, Carter PM, Nation CS, Pizarro JC, Guidry J, Aiyar A, Kelly BL. Cardenas D, et al. Among authors: pizarro jc. Mol Microbiol. 2015 Apr;96(1):95-109. doi: 10.1111/mmi.12924. Epub 2015 Feb 4. Mol Microbiol. 2015. PMID: 25582232 Free PMC article.

3

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.

Whitesell L, Robbins N, Huang DS, McLellan CA, Shekhar-Guturja T, LeBlanc EV, Nation CS, Hui R, Hutchinson A, Collins C, Chatterjee S, Trilles R, Xie JL, Krysan DJ, Lindquist S, Porco JA Jr, Tatu U, Brown LE, Pizarro J, Cowen LE. Whitesell L, et al. Nat Commun. 2019 Jan 24;10(1):402. doi: 10.1038/s41467-018-08248-w. Nat Commun. 2019. PMID: 30679438 Free PMC article.

4

Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs.

Hughes SJ, Antoshchenko T, Chen Y, Lu H, Pizarro JC, Park HW. Hughes SJ, et al. Among authors: pizarro jc. PLoS One. 2016 May 4;11(5):e0154862. doi: 10.1371/journal.pone.0154862. eCollection 2016. PLoS One. 2016. PMID: 27144892 Free PMC article.

5

Correction: Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs.

Hughes SJ, Antoshchenko T, Chen Y, Lu H, Pizarro JC, Park HW. Hughes SJ, et al. Among authors: pizarro jc. PLoS One. 2016 Jun 21;11(6):e0158256. doi: 10.1371/journal.pone.0158256. eCollection 2016. PLoS One. 2016. PMID: 27327447 Free PMC article.

6

Repurposing drugs to target the malaria parasite unfolding protein response.

Chen Y, Murillo-Solano C, Kirkpatrick MG, Antoshchenko T, Park HW, Pizarro JC. Chen Y, et al. Among authors: pizarro jc. Sci Rep. 2018 Jul 9;8(1):10333. doi: 10.1038/s41598-018-28608-2. Sci Rep. 2018. PMID: 29985421 Free PMC article.

7

Design and Synthesis of Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors.

Huang DS, LeBlanc EV, Shekhar-Guturja T, Robbins N, Krysan DJ, Pizarro J, Whitesell L, Cowen LE, Brown LE. Huang DS, et al. J Med Chem. 2020 Mar 12;63(5):2139-2180. doi: 10.1021/acs.jmedchem.9b00826. Epub 2019 Sep 26. J Med Chem. 2020. PMID: 31513387 Free PMC article.

8

Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.

Pizarro JC, Hills T, Senisterra G, Wernimont AK, Mackenzie C, Norcross NR, Ferguson MA, Wyatt PG, Gilbert IH, Hui R. Pizarro JC, et al. PLoS Negl Trop Dis. 2013 Oct 17;7(10):e2492. doi: 10.1371/journal.pntd.0002492. eCollection 2013. PLoS Negl Trop Dis. 2013. PMID: 24147171 Free PMC article.

9

Structures of parasitic CDPK domains point to a common mechanism of activation.

Wernimont AK, Amani M, Qiu W, Pizarro JC, Artz JD, Lin YH, Lew J, Hutchinson A, Hui R. Wernimont AK, et al. Among authors: pizarro jc. Proteins. 2011 Mar;79(3):803-20. doi: 10.1002/prot.22919. Epub 2010 Dec 3. Proteins. 2011. PMID: 21287613

10

The crystal structure of Toxoplasma gondii pyruvate kinase 1.

Bakszt R, Wernimont A, Allali-Hassani A, Mok MW, Hills T, Hui R, Pizarro JC. Bakszt R, et al. Among authors: pizarro jc. PLoS One. 2010 Sep 14;5(9):e12736. doi: 10.1371/journal.pone.0012736. PLoS One. 2010. PMID: 20856875 Free PMC article.

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