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Optimization of Potent and Selective Ataxia Telangiectasia-Mutated Inhibitors Suitable for a Proof-of-Concept Study in Huntington's Disease Models.
J Med Chem. 2019 Mar 28;62(6):2988-3008. doi: 10.1021/acs.jmedchem.8b01819. Epub 2019 Mar 19.
J Med Chem. 2019.
PMID: 30840447
Structure-Based Exploration of Selectivity for ATM Inhibitors in Huntington's Disease.
Van de Poël A, Toledo-Sherman L, Breccia P, Cachope R, Bate JR, Angulo-Herrera I, Wishart G, Matthews KL, Martin SL, Peacock M, Barnard A, Cox HC, Jones G, McAllister G, Vater H, Esmieu W, Clissold C, Lamers M, Leonard P, Jarvis RE, Blackaby W, Eznarriaga M, Lazari O, Yates D, Rose M, Jang SW, Muñoz-Sanjuan I, Dominguez C.
Van de Poël A, et al. Among authors: bate jr.
J Med Chem. 2021 Apr 22;64(8):5018-5036. doi: 10.1021/acs.jmedchem.1c00114. Epub 2021 Mar 30.
J Med Chem. 2021.
PMID: 33783225
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Glycine induces a novel form of long-term potentiation in the superficial layers of the superior colliculus.
Platt B, Bate JR, von Linstow Roloff E, Withington DJ.
Platt B, et al. Among authors: bate jr.
Br J Pharmacol. 1998 Sep;125(2):293-300. doi: 10.1038/sj.bjp.0702062.
Br J Pharmacol. 1998.
PMID: 9786501
Free PMC article.
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