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PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling.
Nawrotek A, Benabdi S, Niyomchon S, Kryszke MH, Ginestier C, Cañeque T, Tepshi L, Mariani A, St Onge RP, Giaever G, Nislow C, Charafe-Jauffret E, Rodriguez R, Zeghouf M, Cherfils J. Nawrotek A, et al. Among authors: tepshi l. Nat Chem Biol. 2019 Apr;15(4):358-366. doi: 10.1038/s41589-019-0228-3. Epub 2019 Feb 11. Nat Chem Biol. 2019. PMID: 30742123
Functional dissection of the retrograde Shiga toxin trafficking inhibitor Retro-2.
Forrester A, Rathjen SJ, Daniela Garcia-Castillo M, Bachert C, Couhert A, Tepshi L, Pichard S, Martinez J, Munier M, Sierocki R, Renard HF, Augusto Valades-Cruz C, Dingli F, Loew D, Lamaze C, Cintrat JC, Linstedt AD, Gillet D, Barbier J, Johannes L. Forrester A, et al. Among authors: tepshi l. Nat Chem Biol. 2020 Mar;16(3):327-336. doi: 10.1038/s41589-020-0474-4. Epub 2020 Feb 17. Nat Chem Biol. 2020. PMID: 32080624 Free PMC article.
MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries.
Ciolek J, Zoukimian C, Dhot J, Burban M, Triquigneaux M, Lauzier B, Guimbert C, Boturyn D, Ferron M, Ciccone L, Tepshi L, Stura E, Legrand P, Robin P, Mourier G, Schaack B, Fellah I, Blanchet G, Gauthier-Erfanian C, Beroud R, Servent D, De Waard M, Gilles N. Ciolek J, et al. Among authors: tepshi l. Biomed Pharmacother. 2022 Jun;150:113094. doi: 10.1016/j.biopha.2022.113094. Epub 2022 May 10. Biomed Pharmacother. 2022. PMID: 35658242 Free article.
Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition.
Mourier G, Salinas M, Kessler P, Stura EA, Leblanc M, Tepshi L, Besson T, Diochot S, Baron A, Douguet D, Lingueglia E, Servent D. Mourier G, et al. Among authors: tepshi l. J Biol Chem. 2016 Feb 5;291(6):2616-29. doi: 10.1074/jbc.M115.702373. Epub 2015 Dec 17. J Biol Chem. 2016. PMID: 26680001 Free PMC article.
Multicomponent mixtures for cryoprotection and ligand solubilization.
Ciccone L, Vera L, Tepshi L, Rosalia L, Rossello A, Stura EA. Ciccone L, et al. Among authors: tepshi l. Biotechnol Rep (Amst). 2015 Jun 23;7:120-127. doi: 10.1016/j.btre.2015.05.008. eCollection 2015 Sep. Biotechnol Rep (Amst). 2015. PMID: 28626721 Free PMC article.
Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies.
Nuti E, Cuffaro D, Bernardini E, Camodeca C, Panelli L, Chaves S, Ciccone L, Tepshi L, Vera L, Orlandini E, Nencetti S, Stura EA, Santos MA, Dive V, Rossello A. Nuti E, et al. Among authors: tepshi l. J Med Chem. 2018 May 24;61(10):4421-4435. doi: 10.1021/acs.jmedchem.8b00096. Epub 2018 May 16. J Med Chem. 2018. PMID: 29727184
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