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Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB.
Oncogene. 2019 Jun;38(25):4962-4976. doi: 10.1038/s41388-019-0767-9. Epub 2019 Mar 4.
Oncogene. 2019.
PMID: 30833638
Free PMC article.
HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species.
Nicholson HE, Tariq Z, Housden BE, Jennings RB, Stransky LA, Perrimon N, Signoretti S, Kaelin WG Jr.
Nicholson HE, et al.
Sci Signal. 2019 Oct 1;12(601):eaay0482. doi: 10.1126/scisignal.aay0482.
Sci Signal. 2019.
PMID: 31575731
Free PMC article.
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Synthetic Lethality Screens Using RNAi in Combination with CRISPR-based Knockout in Drosophila Cells.
Housden BE, Nicholson HE, Perrimon N.
Housden BE, et al. Among authors: nicholson he.
Bio Protoc. 2017 Feb 5;7(3):e2119. doi: 10.21769/BioProtoc.2119.
Bio Protoc. 2017.
PMID: 28523286
Free PMC article.
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pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise.
Reddy A, Bozi LHM, Yaghi OK, Mills EL, Xiao H, Nicholson HE, Paschini M, Paulo JA, Garrity R, Laznik-Bogoslavski D, Ferreira JCB, Carl CS, Sjøberg KA, Wojtaszewski JFP, Jeppesen JF, Kiens B, Gygi SP, Richter EA, Mathis D, Chouchani ET.
Reddy A, et al. Among authors: nicholson he.
Cell. 2020 Oct 1;183(1):62-75.e17. doi: 10.1016/j.cell.2020.08.039. Epub 2020 Sep 17.
Cell. 2020.
PMID: 32946811
Free PMC article.
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Identification and characterization of MAM03055A: A novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity.
Liu CZ, Mottinelli M, Nicholson HE, McVeigh BM, Wong NK, McCurdy CR, Bowen WD.
Liu CZ, et al. Among authors: nicholson he.
Eur J Pharmacol. 2021 Sep 5;906:174263. doi: 10.1016/j.ejphar.2021.174263. Epub 2021 Jun 16.
Eur J Pharmacol. 2021.
PMID: 34144027
Free PMC article.
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Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-Activity Relationships of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives.
Nicholson HE, Alsharif WF, Comeau AB, Mesangeau C, Intagliata S, Mottinelli M, McCurdy CR, Bowen WD.
Nicholson HE, et al.
J Pharmacol Exp Ther. 2019 Feb;368(2):272-281. doi: 10.1124/jpet.118.253484. Epub 2018 Dec 7.
J Pharmacol Exp Ther. 2019.
PMID: 30530624
Free PMC article.
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