Pennati M - Search Results

1

Rational design of allosteric modulators of the aromatase enzyme: An unprecedented therapeutic strategy to fight breast cancer.

Spinello A, Martini S, Berti F, Pennati M, Pavlin M, Sgrignani J, Grazioso G, Colombo G, Zaffaroni N, Magistrato A. Spinello A, et al. Among authors: pennati m. Eur J Med Chem. 2019 Apr 15;168:253-262. doi: 10.1016/j.ejmech.2019.02.045. Epub 2019 Feb 13. Eur J Med Chem. 2019. PMID: 30822713 Free article.

2

Small-molecule targeting of heat shock protein 90 chaperone function: rational identification of a new anticancer lead.

Meli M, Pennati M, Curto M, Daidone MG, Plescia J, Toba S, Altieri DC, Zaffaroni N, Colombo G. Meli M, et al. Among authors: pennati m. J Med Chem. 2006 Dec 28;49(26):7721-30. doi: 10.1021/jm060836y. J Med Chem. 2006. PMID: 17181154

3

A Computational Assay of Estrogen Receptor α Antagonists Reveals the Key Common Structural Traits of Drugs Effectively Fighting Refractory Breast Cancers.

Pavlin M, Spinello A, Pennati M, Zaffaroni N, Gobbi S, Bisi A, Colombo G, Magistrato A. Pavlin M, et al. Among authors: pennati m. Sci Rep. 2018 Jan 12;8(1):649. doi: 10.1038/s41598-017-17364-4. Sci Rep. 2018. PMID: 29330437 Free PMC article.

4

RNA interference-mediated validation of survivin and Apollon/BRUCE as new therapeutic targets for cancer therapy.

Pennati M, Millo E, Gandellini P, Folini M, Zaffaroni N. Pennati M, et al. Curr Top Med Chem. 2012;12(2):69-78. doi: 10.2174/156802612798919169. Curr Top Med Chem. 2012. PMID: 22196277 Review.

5

Novel 1H-pyrrolo[2,3-b]pyridine derivative nortopsentin analogues: synthesis and antitumor activity in peritoneal mesothelioma experimental models.

Carbone A, Pennati M, Parrino B, Lopergolo A, Barraja P, Montalbano A, Spanò V, Sbarra S, Doldi V, De Cesare M, Cirrincione G, Diana P, Zaffaroni N. Carbone A, et al. Among authors: pennati m. J Med Chem. 2013 Sep 12;56(17):7060-72. doi: 10.1021/jm400842x. Epub 2013 Aug 23. J Med Chem. 2013. PMID: 23919303

6

Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: in vitro antiproliferative activity and molecular mechanism(s) of action.

Parrino B, Carbone A, Ciancimino C, Spanò V, Montalbano A, Barraja P, Cirrincione G, Diana P, Sissi C, Palumbo M, Pinato O, Pennati M, Beretta G, Folini M, Matyus P, Balogh B, Zaffaroni N. Parrino B, et al. Among authors: pennati m. Eur J Med Chem. 2015 Apr 13;94:149-62. doi: 10.1016/j.ejmech.2015.03.005. Epub 2015 Mar 5. Eur J Med Chem. 2015. PMID: 25768699

7

Preclinical Activity of New [1,2]Oxazolo[5,4-e]isoindole Derivatives in Diffuse Malignant Peritoneal Mesothelioma.

Spanò V, Pennati M, Parrino B, Carbone A, Montalbano A, Cilibrasi V, Zuco V, Lopergolo A, Cominetti D, Diana P, Cirrincione G, Barraja P, Zaffaroni N. Spanò V, et al. Among authors: pennati m. J Med Chem. 2016 Aug 11;59(15):7223-38. doi: 10.1021/acs.jmedchem.6b00777. Epub 2016 Jul 26. J Med Chem. 2016. PMID: 27428868

8

[1,2]Oxazolo[5,4-e]isoindoles as promising tubulin polymerization inhibitors.

Spanò V, Pennati M, Parrino B, Carbone A, Montalbano A, Lopergolo A, Zuco V, Cominetti D, Diana P, Cirrincione G, Zaffaroni N, Barraja P. Spanò V, et al. Among authors: pennati m. Eur J Med Chem. 2016 Nov 29;124:840-851. doi: 10.1016/j.ejmech.2016.09.013. Epub 2016 Sep 5. Eur J Med Chem. 2016. PMID: 27643641

9

Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

D'Annessa I, Sattin S, Tao J, Pennati M, Sànchez-Martìn C, Moroni E, Rasola A, Zaffaroni N, Agard DA, Bernardi A, Colombo G. D'Annessa I, et al. Among authors: pennati m. Chemistry. 2017 Apr 19;23(22):5188-5192. doi: 10.1002/chem.201700169. Epub 2017 Mar 22. Chemistry. 2017. PMID: 28207175 Free PMC article.

10

Targeting survivin in cancer therapy: fulfilled promises and open questions.

Pennati M, Folini M, Zaffaroni N. Pennati M, et al. Carcinogenesis. 2007 Jun;28(6):1133-9. doi: 10.1093/carcin/bgm047. Epub 2007 Mar 6. Carcinogenesis. 2007. PMID: 17341657 Review.

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