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The proteostasis network provides targets for neurodegeneration.
Br J Pharmacol. 2019 Sep;176(18):3508-3514. doi: 10.1111/bph.14643. Epub 2019 May 23.
Br J Pharmacol. 2019.
PMID: 30820936
Free PMC article.
Review.
Sterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB.
Roussel BD, Newton TM, Malzer E, Simecek N, Haq I, Thomas SE, Burr ML, Lehner PJ, Crowther DC, Marciniak SJ, Lomas DA.
Roussel BD, et al. Among authors: newton tm.
Hum Mol Genet. 2013 Nov 15;22(22):4616-26. doi: 10.1093/hmg/ddt310. Epub 2013 Jun 28.
Hum Mol Genet. 2013.
PMID: 23814041
Free PMC article.
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Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia.
Allison R, Edgar JR, Pearson G, Rizo T, Newton T, Günther S, Berner F, Hague J, Connell JW, Winkler J, Lippincott-Schwartz J, Beetz C, Winner B, Reid E.
Allison R, et al.
J Cell Biol. 2017 May 1;216(5):1337-1355. doi: 10.1083/jcb.201609033. Epub 2017 Apr 7.
J Cell Biol. 2017.
PMID: 28389476
Free PMC article.
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Mechanistic basis of an epistatic interaction reducing age at onset in hereditary spastic paraplegia.
Newton T, Allison R, Edgar JR, Lumb JH, Rodger CE, Manna PT, Rizo T, Kohl Z, Nygren AOH, Arning L, Schüle R, Depienne C, Goldberg L, Frahm C, Stevanin G, Durr A, Schöls L, Winner B, Beetz C, Reid E.
Newton T, et al.
Brain. 2018 May 1;141(5):1286-1299. doi: 10.1093/brain/awy034.
Brain. 2018.
PMID: 29481671
Free PMC article.
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An Automated Image Analysis System to Quantify Endosomal Tubulation.
Newton TM, Reid E.
Newton TM, et al.
PLoS One. 2016 Dec 22;11(12):e0168294. doi: 10.1371/journal.pone.0168294. eCollection 2016.
PLoS One. 2016.
PMID: 28006827
Free PMC article.
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Observations on a Case of Retroperitoneal Sarcoma.
Newton TM.
Newton TM.
Glasgow Med J. 1932 Mar;117(3):136-138.
Glasgow Med J. 1932.
PMID: 30438429
Free PMC article.
No abstract available.
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