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Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity.
von Geldern TW, Morton HE, Clark RF, Brown BS, Johnston KL, Ford L, Specht S, Carr RA, Stolarik DF, Ma J, Rieser MJ, Struever D, Frohberger SJ, Koschel M, Ehrens A, Turner JD, Hübner MP, Hoerauf A, Taylor MJ, Ward SA, Marsh K, Kempf DJ. von Geldern TW, et al. Among authors: specht s. PLoS Negl Trop Dis. 2019 Feb 28;13(2):e0007159. doi: 10.1371/journal.pntd.0007159. eCollection 2019 Feb. PLoS Negl Trop Dis. 2019. PMID: 30818326 Free PMC article.
Immunomodulation by filarial nematodes.
Hoerauf A, Satoguina J, Saeftel M, Specht S. Hoerauf A, et al. Among authors: specht s. Parasite Immunol. 2005 Oct-Nov;27(10-11):417-29. doi: 10.1111/j.1365-3024.2005.00792.x. Parasite Immunol. 2005. PMID: 16179035 Review.
241 results