Elmore CS - Search Results

1

Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT_1B receptors.

Lindberg A, Lu S, Nag S, Schou M, Liow JS, Zoghbi SS, Frankland MP, Gladding RL, Morse CL, Takano A, Amini N, Elmore CS, Lee YS, Innis RB, Halldin C, Pike VW. Lindberg A, et al. Among authors: elmore cs. Nucl Med Biol. 2019 Mar;70:1-13. doi: 10.1016/j.nucmedbio.2019.01.005. Epub 2019 Jan 26. Nucl Med Biol. 2019. PMID: 30811975 Free PMC article.

2

Development of a PET radioligand for the central 5-HT1B receptor: radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds.

Andersson JD, Pierson ME, Finnema SJ, Gulyás B, Heys R, Elmore CS, Farde L, Halldin C. Andersson JD, et al. Among authors: elmore cs. Nucl Med Biol. 2011 Feb;38(2):261-72. doi: 10.1016/j.nucmedbio.2010.08.006. Epub 2010 Dec 3. Nucl Med Biol. 2011. PMID: 21315282

3

Development of new carbon-11 labelled radiotracers for imaging GABAA- and GABAB-benzodiazepine receptors.

Moran MD, Wilson AA, Elmore CS, Parkes J, Ng A, Sadovski O, Graff A, Daskalakis ZJ, Houle S, Chapdelaine MJ, Vasdev N. Moran MD, et al. Among authors: elmore cs. Bioorg Med Chem. 2012 Jul 15;20(14):4482-8. doi: 10.1016/j.bmc.2012.05.046. Epub 2012 May 24. Bioorg Med Chem. 2012. PMID: 22717238

4

[¹¹C]AZ10419096 - a full antagonist PET radioligand for imaging brain 5-HT_1B receptors.

Lindberg A, Nag S, Schou M, Takano A, Matsumoto J, Amini N, Elmore CS, Farde L, Pike VW, Halldin C. Lindberg A, et al. Among authors: elmore cs. Nucl Med Biol. 2017 Nov;54:34-40. doi: 10.1016/j.nucmedbio.2017.07.007. Epub 2017 Jul 21. Nucl Med Biol. 2017. PMID: 28950161

5

Increased Brain Exposure of an Alpha-Synuclein Fibrillization Modulator by Utilization of an Activated Ester Prodrug Strategy.

Cairns AG, Vazquez-Romero A, Mahdi Moein M, Ådén J, Elmore CS, Takano A, Arakawa R, Varrone A, Almqvist F, Schou M. Cairns AG, et al. Among authors: elmore cs. ACS Chem Neurosci. 2018 Nov 21;9(11):2542-2547. doi: 10.1021/acschemneuro.8b00236. Epub 2018 Jun 19. ACS Chem Neurosci. 2018. PMID: 29901990

6

Synthesis, ³ H-labelling and in vitro evaluation of a substituted dipiperidine alcohol as a potential ligand for chemokine receptor 2.

Artelsmair M, Miranda-Azpiazu P, Kingston L, Bergare J, Schou M, Varrone A, Elmore CS. Artelsmair M, et al. Among authors: elmore cs. J Labelled Comp Radiopharm. 2019 May 30;62(6):265-279. doi: 10.1002/jlcr.3731. J Labelled Comp Radiopharm. 2019. PMID: 30937946 Free PMC article.

7

The synthesis of isotopologues of AZD7307: A selective β₂ -adrenoreceptor agonist.

Kingston LP, Hickey MJ, Elmore CS. Kingston LP, et al. Among authors: elmore cs. J Labelled Comp Radiopharm. 2019 Sep;62(11):707-712. doi: 10.1002/jlcr.3778. Epub 2019 Jul 19. J Labelled Comp Radiopharm. 2019. PMID: 31215663

8

The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans.

Varnäs K, Cselényi Z, Arakawa R, Nag S, Stepanov V, Moein MM, Johnström P, Kingston L, Elmore CS, Halldin C, Farde L. Varnäs K, et al. Among authors: elmore cs. Neuropharmacology. 2020 Jan 1;162:107809. doi: 10.1016/j.neuropharm.2019.107809. Epub 2019 Oct 4. Neuropharmacology. 2020. PMID: 31589885 Free article.

9

Development of a ¹⁸F-labeled PET radioligand for imaging 5-HT_1B receptors: [¹⁸F]AZ10419096.

Lindberg A, Nag S, Schou M, Arakawa R, Nogami T, Moein MM, Elmore CS, Pike VW, Halldin C. Lindberg A, et al. Among authors: elmore cs. Nucl Med Biol. 2019 Nov-Dec;78-79:11-16. doi: 10.1016/j.nucmedbio.2019.10.003. Epub 2019 Oct 22. Nucl Med Biol. 2019. PMID: 31678782 Free PMC article.

10

Potential for imaging the high-affinity state of the 5-HT_1B receptor: a comparison of three PET radioligands with differing intrinsic activity.

Lindberg A, Arakawa R, Nogami T, Nag S, Schou M, Elmore CS, Farde L, Pike VW, Halldin C. Lindberg A, et al. Among authors: elmore cs. EJNMMI Res. 2019 Nov 21;9(1):100. doi: 10.1186/s13550-019-0570-1. EJNMMI Res. 2019. PMID: 31754940 Free PMC article.

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