Ran C - Search Results

1

Dual blockade of CXCL12-CXCR4 and PD-1-PD-L1 pathways prolongs survival of ovarian tumor-bearing mice by prevention of immunosuppression in the tumor microenvironment.

Zeng Y, Li B, Liang Y, Reeves PM, Qu X, Ran C, Liu Q, Callahan MV, Sluder AE, Gelfand JA, Chen H, Poznansky MC. Zeng Y, et al. Among authors: ran c. FASEB J. 2019 May;33(5):6596-6608. doi: 10.1096/fj.201802067RR. Epub 2019 Feb 25. FASEB J. 2019. PMID: 30802149 Free PMC article.

We found that AMD3100, a highly specific CXCR4 antagonist, directly down-regulated the expression of both C-X-C motif chemokine 12 (CXCL12) and CXCR4 in vitro and in vivo in tumor cells. ...These results suggest that AMD3100 could be used to target the CXCR4-CXCL12 …

We found that AMD3100, a highly specific CXCR4 antagonist, directly down-regulated the expression of both C-X-C motif chemokin …

2

AMD3100 Augments the Efficacy of Mesothelin-Targeted, Immune-Activating VIC-008 in Mesothelioma by Modulating Intratumoral Immunosuppression.

Li B, Zeng Y, Reeves PM, Ran C, Liu Q, Qu X, Liang Y, Liu Z, Yuan J, Leblanc PR, Ye Z, Sluder AE, Gelfand JA, Brauns TA, Chen H, Poznansky MC. Li B, et al. Among authors: ran c. Cancer Immunol Res. 2018 May;6(5):539-551. doi: 10.1158/2326-6066.CIR-17-0530. Epub 2018 Mar 6. Cancer Immunol Res. 2018. PMID: 29511032

3

CD90^low MSCs modulate intratumoral immunity to confer antitumor activity in a mouse model of ovarian cancer.

Zeng Y, Li B, Li T, Liu W, Ran C, Penson RT, Poznansky MC, Du Y, Chen H. Zeng Y, et al. Among authors: ran c. Oncotarget. 2019 Jul 9;10(43):4479-4491. doi: 10.18632/oncotarget.27065. eCollection 2019 Jul 9. Oncotarget. 2019. PMID: 31320999 Free PMC article.

4

Novel radioligands for imaging sigma-1 receptor in brain using positron emission tomography (PET).

Lan Y, Bai P, Chen Z, Neelamegam R, Placzek MS, Wang H, Fiedler SA, Yang J, Yuan G, Qu X, Schmidt HR, Song J, Normandin MD, Ran C, Wang C. Lan Y, et al. Among authors: ran c. Acta Pharm Sin B. 2019 Nov;9(6):1204-1215. doi: 10.1016/j.apsb.2019.07.002. Epub 2019 Jul 11. Acta Pharm Sin B. 2019. PMID: 31867166 Free PMC article.

5

Imaging assisted evaluation of antitumor efficacy of a new histone deacetylase inhibitor in the castration-resistant prostate cancer.

Chen Z, Wang X, Yang X, Xu Y, Yang Y, Wang H, Li T, Bai P, Yuan G, Chen H, Yang J, Fiedler SA, Striar R, Bernales DR, Koegel RE, Cao Q, Ran C, Xiang B, Li H, Wang C. Chen Z, et al. Among authors: ran c. Eur J Nucl Med Mol Imaging. 2021 Jan;48(1):53-66. doi: 10.1007/s00259-020-04896-7. Epub 2020 Jun 26. Eur J Nucl Med Mol Imaging. 2021. PMID: 32592040

6

Novel conjugates of endoperoxide and 4-anilinoquinazoline as potential anticancer agents.

Yang J, Tu Z, Xu X, Luo J, Yan X, Ran C, Mao X, Ding K, Qiao C. Yang J, et al. Among authors: ran c. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1341-1345. doi: 10.1016/j.bmcl.2017.02.023. Epub 2017 Feb 13. Bioorg Med Chem Lett. 2017. PMID: 28236592

7

A Curcumin Analog Reduces Levels of the Alzheimer's Disease-Associated Amyloid-β Protein by Modulating AβPP Processing and Autophagy.

Wan Y, Liang Y, Liang F, Shen N, Shinozuka K, Yu JT, Ran C, Quan Q, Tanzi RE, Zhang C. Wan Y, et al. Among authors: ran c. J Alzheimers Dis. 2019;72(3):761-771. doi: 10.3233/JAD-190562. J Alzheimers Dis. 2019. PMID: 31640096

8

Molecular imaging of Alzheimer's disease-related gamma-secretase in mice and nonhuman primates.

Xu Y, Wang C, Wey HY, Liang Y, Chen Z, Choi SH, Ran C, Rynearson KD, Bernales DR, Koegel RE, Fiedler SA, Striar R, Wagner SL, Tanzi RE, Zhang C. Xu Y, et al. Among authors: ran c. J Exp Med. 2020 Dec 7;217(12):e20182266. doi: 10.1084/jem.20182266. J Exp Med. 2020. PMID: 32936886 Free PMC article.

9

Design and synthesis of curcumin analogues for in vivo fluorescence imaging and inhibiting copper-induced cross-linking of amyloid beta species in Alzheimer's disease.

Zhang X, Tian Y, Li Z, Tian X, Sun H, Liu H, Moore A, Ran C. Zhang X, et al. Among authors: ran c. J Am Chem Soc. 2013 Nov 6;135(44):16397-409. doi: 10.1021/ja405239v. Epub 2013 Oct 25. J Am Chem Soc. 2013. PMID: 24116384 Free PMC article.

10

Cromolyn Reduces Levels of the Alzheimer's Disease-Associated Amyloid β-Protein by Promoting Microglial Phagocytosis.

Zhang C, Griciuc A, Hudry E, Wan Y, Quinti L, Ward J, Forte AM, Shen X, Ran C, Elmaleh DR, Tanzi RE. Zhang C, et al. Among authors: ran c. Sci Rep. 2018 Jan 18;8(1):1144. doi: 10.1038/s41598-018-19641-2. Sci Rep. 2018. PMID: 29348604 Free PMC article.

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