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Page 1
New Copper Compounds with Antiplatelet Aggregation Activity.
Flores-García M, Fernández-G JM, Busqueta-Griera C, Gómez E, Hernández-Ortega S, Lamothe-Flores JCD, Gómez-Vidales V, Mejía-Domínguez AM, Anglés-Cano E, de la Peña-Díaz A. Flores-García M, et al. Among authors: fernandez g jm. Med Chem. 2019;15(8):850-862. doi: 10.2174/1573406415666190222123207. Med Chem. 2019. PMID: 30799791
The structures and inhibitory effects of Buame [N-(3-hydroxy-1,3,5(10)-estratrien-17β-yl)-butylamine] and Diebud [N,N'-bis-(3-hydroxy-1,3,5(10)-estratrien-17β-yl)-1,4-butanediamine] on platelet aggregation.
Flores-García M, Fernández-G JM, León-Martínez M, Hernández-Ortega S, Pérez-Méndez O, Correa-Basurto J, Carreón-Torres E, Tolentino-López LE, Ceballos-Reyes GM, de la Peña-Díaz A. Flores-García M, et al. Among authors: fernandez g jm. Steroids. 2012 Apr;77(5):512-20. doi: 10.1016/j.steroids.2012.01.010. Epub 2012 Feb 2. Steroids. 2012. PMID: 22326683
The antithrombotic effect of the aminoestrogen prolame (N-(3-hydroxy-1,3,5(10)-estratrien-17B-YL)-3-hydroxypropylamine) is linked to an increase in nitric oxide production by platelets and endothelial cells.
González G, Alvarado-Vasquez N, Fernández-G JM, Cruz-Robles D, Del Valle L, Pinzón E, Torres I, Rodriguez E, Zapata E, Gómez-Vidales V, Montaño LF, de la Peña A. González G, et al. Among authors: fernandez g jm. Atherosclerosis. 2010 Jan;208(1):62-8. doi: 10.1016/j.atherosclerosis.2009.06.017. Epub 2009 Jun 18. Atherosclerosis. 2010. PMID: 19615684
Neuroprotective effect of the aminoestrogen prolame against impairment of learning and memory skills in rats injected with amyloid-β-25-35 into the hippocampus.
Limón D, Díaz A, Hernandez M, Fernandez-G JM, Torres-Martínez AC, Pérez-Severiano F, Rendón-Huerta EP, Montaño LF, Guevara J. Limón D, et al. Among authors: fernandez g jm. Eur J Pharmacol. 2012 Jun 15;685(1-3):74-80. doi: 10.1016/j.ejphar.2012.04.020. Epub 2012 Apr 20. Eur J Pharmacol. 2012. PMID: 22542664
Reduction of no-reflow and reperfusion injury with the synthetic 17β-aminoestrogen compound Prolame is associated with PI3K/Akt/eNOS signaling cascade.
Hernández-Reséndiz S, Palma-Flores C, De Los Santos S, Román-Anguiano NG, Flores M, de la Peña A, Flores PL, Fernández-G JM, Coral-Vázquez RM, Zazueta C. Hernández-Reséndiz S, et al. Among authors: fernandez g jm. Basic Res Cardiol. 2015 Mar;110(2):1. doi: 10.1007/s00395-015-0464-y. Epub 2015 Jan 15. Basic Res Cardiol. 2015. PMID: 25589055