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Identification of C-6 as a New Site for Linker Conjugation to the Taccalonolide Microtubule Stabilizers.
J Nat Prod. 2019 Mar 22;82(3):583-588. doi: 10.1021/acs.jnatprod.8b01036. Epub 2019 Feb 25.
J Nat Prod. 2019.
PMID: 30799622
Free PMC article.
Taccalonolide Microtubule Stabilizers Generated Using Semisynthesis Define the Effects of Mono Acyloxy Moieties at C-7 or C-15 and Disubstitutions at C-7 and C-25.
Ola ARB, Risinger AL, Du L, Zammiello CL, Peng J, Cichewicz RH, Mooberry SL.
Ola ARB, et al. Among authors: zammiello cl.
J Nat Prod. 2018 Mar 23;81(3):579-593. doi: 10.1021/acs.jnatprod.7b00967. Epub 2018 Jan 23.
J Nat Prod. 2018.
PMID: 29360362
Free PMC article.
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The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agents.
Zhang X, Raghavan S, Ihnat M, Hamel E, Zammiello C, Bastian A, Mooberry SL, Gangjee A.
Zhang X, et al.
Bioorg Med Chem. 2015 May 15;23(10):2408-23. doi: 10.1016/j.bmc.2015.03.061. Epub 2015 Mar 30.
Bioorg Med Chem. 2015.
PMID: 25882519
Free PMC article.
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