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CRISPR/Cas9 genome engineering in hematopoietic cells.
Sürün D, von Melchner H, Schnütgen F. Sürün D, et al. Among authors: von melchner h. Drug Discov Today Technol. 2018 Aug;28:33-39. doi: 10.1016/j.ddtec.2018.08.001. Epub 2018 Aug 25. Drug Discov Today Technol. 2018. PMID: 30205879 Free article. Review.
Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.
Tomasovic A, Kurrle N, Sürün D, Heidler J, Husnjak K, Poser I, Schnütgen F, Scheibe S, Seimetz M, Jaksch P, Hyman A, Weissmann N, von Melchner H. Tomasovic A, et al. Among authors: von melchner h. J Biol Chem. 2015 Apr 10;290(15):9738-52. doi: 10.1074/jbc.M114.632133. Epub 2015 Feb 25. J Biol Chem. 2015. PMID: 25716320 Free PMC article.
Engineering embryonic stem cells with recombinase systems.
Schnütgen F, Stewart AF, von Melchner H, Anastassiadis K. Schnütgen F, et al. Among authors: von melchner h. Methods Enzymol. 2006;420:100-36. doi: 10.1016/S0076-6879(06)20007-7. Methods Enzymol. 2006. PMID: 17161696
Enhanced gene trapping in mouse embryonic stem cells.
Schnütgen F, Hansen J, De-Zolt S, Horn C, Lutz M, Floss T, Wurst W, Noppinger PR, von Melchner H. Schnütgen F, et al. Among authors: von melchner h. Nucleic Acids Res. 2008 Nov;36(20):e133. doi: 10.1093/nar/gkn603. Epub 2008 Sep 23. Nucleic Acids Res. 2008. PMID: 18812397 Free PMC article.
Gene-trap vectors and mutagenesis.
De-Zolt S, Altschmied J, Ruiz P, von Melchner H, Schnütgen F. De-Zolt S, et al. Among authors: von melchner h. Methods Mol Biol. 2009;530:29-47. doi: 10.1007/978-1-59745-471-1_3. Methods Mol Biol. 2009. PMID: 19266330
85 results