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Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.
Kurelac I, Iommarini L, Vatrinet R, Amato LB, De Luise M, Leone G, Girolimetti G, Umesh Ganesh N, Bridgeman VL, Ombrato L, Columbaro M, Ragazzi M, Gibellini L, Sollazzo M, Feichtinger RG, Vidali S, Baldassarre M, Foriel S, Vidone M, Cossarizza A, Grifoni D, Kofler B, Malanchi I, Porcelli AM, Gasparre G. Kurelac I, et al. Among authors: de luise m. Nat Commun. 2019 Feb 22;10(1):903. doi: 10.1038/s41467-019-08839-1. Nat Commun. 2019. PMID: 30796225 Free PMC article.
Targeting respiratory complex I to prevent the Warburg effect.
Vatrinet R, Iommarini L, Kurelac I, De Luise M, Gasparre G, Porcelli AM. Vatrinet R, et al. Among authors: de luise m. Int J Biochem Cell Biol. 2015 Jun;63:41-5. doi: 10.1016/j.biocel.2015.01.017. Epub 2015 Feb 7. Int J Biochem Cell Biol. 2015. PMID: 25668477 Review.
The α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity.
Vatrinet R, Leone G, De Luise M, Girolimetti G, Vidone M, Gasparre G, Porcelli AM. Vatrinet R, et al. Among authors: de luise m. Cancer Metab. 2017 Feb 2;5:3. doi: 10.1186/s40170-017-0165-0. eCollection 2017. Cancer Metab. 2017. PMID: 28184304 Free PMC article. Review.
Pathogenic Mitochondrial DNA Mutation Load Inversely Correlates with Malignant Features in Familial Oncocytic Parathyroid Tumors Associated with Hyperparathyroidism-Jaw Tumor Syndrome.
De Luise M, Iommarini L, Marchio L, Tedesco G, Coadă CA, Repaci A, Turchetti D, Tardio ML, Salfi N, Pagotto U, Kurelac I, Porcelli AM, Gasparre G. De Luise M, et al. Cells. 2021 Oct 28;10(11):2920. doi: 10.3390/cells10112920. Cells. 2021. PMID: 34831144 Free PMC article.
Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer.
De Luise M, Sollazzo M, Lama E, Coadă CA, Bressi L, Iorio M, Cavina B, D'Angelo L, Milioni S, Marchio L, Miglietta S, Coluccelli S, Tedesco G, Ghelli A, Lemma S, Perrone AM, Kurelac I, Iommarini L, Porcelli AM, Gasparre G. De Luise M, et al. Sci Rep. 2022 May 16;12(1):8020. doi: 10.1038/s41598-022-11620-y. Sci Rep. 2022. PMID: 35577908 Free PMC article.
60 results