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Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function.
Lumsden EW, Troppoli TA, Myers SJ, Zanos P, Aracava Y, Kehr J, Lovett J, Kim S, Wang FH, Schmidt S, Jenne CE, Yuan P, Morris PJ, Thomas CJ, Zarate CA Jr, Moaddel R, Traynelis SF, Pereira EFR, Thompson SM, Albuquerque EX, Gould TD. Lumsden EW, et al. Among authors: myers sj. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5160-5169. doi: 10.1073/pnas.1816071116. Epub 2019 Feb 22. Proc Natl Acad Sci U S A. 2019. PMID: 30796190 Free PMC article.
Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists.
Tahirovic YA, Geballe M, Gruszecka-Kowalik E, Myers SJ, Lyuboslavsky P, Le P, French A, Irier H, Choi WB, Easterling K, Yuan H, Wilson LJ, Kotloski R, McNamara JO, Dingledine R, Liotta DC, Traynelis SF, Snyder JP. Tahirovic YA, et al. Among authors: myers sj. J Med Chem. 2008 Sep 25;51(18):5506-21. doi: 10.1021/jm8002153. J Med Chem. 2008. PMID: 18800760 Free PMC article.
Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors.
Mosley CA, Myers SJ, Murray EE, Santangelo R, Tahirovic YA, Kurtkaya N, Mullasseril P, Yuan H, Lyuboslavsky P, Le P, Wilson LJ, Yepes M, Dingledine R, Traynelis SF, Liotta DC. Mosley CA, et al. Among authors: myers sj. Bioorg Med Chem. 2009 Sep 1;17(17):6463-80. doi: 10.1016/j.bmc.2009.05.085. Epub 2009 Jul 5. Bioorg Med Chem. 2009. PMID: 19648014 Free PMC article.
Glutamate receptor ion channels: structure, regulation, and function.
Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R. Traynelis SF, et al. Among authors: myers sj. Pharmacol Rev. 2010 Sep;62(3):405-96. doi: 10.1124/pr.109.002451. Pharmacol Rev. 2010. PMID: 20716669 Free PMC article. Review.
Human GRIN2B variants in neurodevelopmental disorders.
Hu C, Chen W, Myers SJ, Yuan H, Traynelis SF. Hu C, et al. Among authors: myers sj. J Pharmacol Sci. 2016 Oct;132(2):115-121. doi: 10.1016/j.jphs.2016.10.002. Epub 2016 Oct 19. J Pharmacol Sci. 2016. PMID: 27818011 Free PMC article. Review.
A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons.
Swanger SA, Vance KM, Acker TM, Zimmerman SS, DiRaddo JO, Myers SJ, Bundgaard C, Mosley CA, Summer SL, Menaldino DS, Jensen HS, Liotta DC, Traynelis SF. Swanger SA, et al. Among authors: myers sj. ACS Chem Neurosci. 2018 Feb 21;9(2):306-319. doi: 10.1021/acschemneuro.7b00329. Epub 2017 Nov 2. ACS Chem Neurosci. 2018. PMID: 29043770 Free PMC article.
A novel missense mutation in GRIN2A causes a nonepileptic neurodevelopmental disorder.
Fernández-Marmiesse A, Kusumoto H, Rekarte S, Roca I, Zhang J, Myers SJ, Traynelis SF, Couce ML, Gutierrez-Solana L, Yuan H. Fernández-Marmiesse A, et al. Among authors: myers sj. Mov Disord. 2018 Jul;33(6):992-999. doi: 10.1002/mds.27315. Epub 2018 Apr 11. Mov Disord. 2018. PMID: 29644724 Free PMC article.
109 results