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Neurodegeneration, Heterochromatin, and Double-Stranded RNA.
Saldi TK, Gonzales PK, LaRocca TJ, Link CD. Saldi TK, et al. Among authors: link cd. J Exp Neurosci. 2019 Feb 14;13:1179069519830697. doi: 10.1177/1179069519830697. eCollection 2019. J Exp Neurosci. 2019. PMID: 30792577 Free PMC article. Review.
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity.
Zhang YJ, Guo L, Gonzales PK, Gendron TF, Wu Y, Jansen-West K, O'Raw AD, Pickles SR, Prudencio M, Carlomagno Y, Gachechiladze MA, Ludwig C, Tian R, Chew J, DeTure M, Lin WL, Tong J, Daughrity LM, Yue M, Song Y, Andersen JW, Castanedes-Casey M, Kurti A, Datta A, Antognetti G, McCampbell A, Rademakers R, Oskarsson B, Dickson DW, Kampmann M, Ward ME, Fryer JD, Link CD, Shorter J, Petrucelli L. Zhang YJ, et al. Among authors: link cd. Science. 2019 Feb 15;363(6428):eaav2606. doi: 10.1126/science.aav2606. Science. 2019. PMID: 30765536 Free PMC article.
Amyloid beta acts synergistically as a pro-inflammatory cytokine.
LaRocca TJ, Cavalier AN, Roberts CM, Lemieux MR, Ramesh P, Garcia MA, Link CD. LaRocca TJ, et al. Among authors: link cd. Neurobiol Dis. 2021 Nov;159:105493. doi: 10.1016/j.nbd.2021.105493. Epub 2021 Aug 28. Neurobiol Dis. 2021. PMID: 34464705 Free PMC article.
Development. Cell death by glutamine repeats?
Link CD, Saldi TK. Link CD, et al. Science. 2012 Feb 24;335(6071):926-7. doi: 10.1126/science.1219834. Science. 2012. PMID: 22362996 No abstract available.
Repetitive element transcripts are elevated in the brain of C9orf72 ALS/FTLD patients.
Prudencio M, Gonzales PK, Cook CN, Gendron TF, Daughrity LM, Song Y, Ebbert MTW, van Blitterswijk M, Zhang YJ, Jansen-West K, Baker MC, DeTure M, Rademakers R, Boylan KB, Dickson DW, Petrucelli L, Link CD. Prudencio M, et al. Among authors: link cd. Hum Mol Genet. 2017 Sep 1;26(17):3421-3431. doi: 10.1093/hmg/ddx233. Hum Mol Genet. 2017. PMID: 28637276 Free PMC article.
95 results