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Outcomes of controlled human malaria infection after BCG vaccination.
Walk J, de Bree LCJ, Graumans W, Stoter R, van Gemert GJ, van de Vegte-Bolmer M, Teelen K, Hermsen CC, Arts RJW, Behet MC, Keramati F, Moorlag SJCFM, Yang ASP, van Crevel R, Aaby P, de Mast Q, van der Ven AJAM, Stabell Benn C, Netea MG, Sauerwein RW. Walk J, et al. Among authors: yang asp. Nat Commun. 2019 Feb 20;10(1):874. doi: 10.1038/s41467-019-08659-3. Nat Commun. 2019. PMID: 30787276 Free PMC article. Clinical Trial.
A Plasmodium berghei sporozoite-based vaccination platform against human malaria.
Mendes AM, Machado M, Gonçalves-Rosa N, Reuling IJ, Foquet L, Marques C, Salman AM, Yang ASP, Moser KA, Dwivedi A, Hermsen CC, Jiménez-Díaz B, Viera S, Santos JM, Albuquerque I, Bhatia SN, Bial J, Angulo-Barturen I, Silva JC, Leroux-Roels G, Janse CJ, Khan SM, Mota MM, Sauerwein RW, Prudêncio M. Mendes AM, et al. Among authors: yang asp. NPJ Vaccines. 2018 Aug 24;3:33. doi: 10.1038/s41541-018-0068-2. eCollection 2018. NPJ Vaccines. 2018. PMID: 30155278 Free PMC article.
An open-label phase 1/2a trial of a genetically modified rodent malaria parasite for immunization against Plasmodium falciparum malaria.
Reuling IJ, Mendes AM, de Jong GM, Fabra-García A, Nunes-Cabaço H, van Gemert GJ, Graumans W, Coffeng LE, de Vlas SJ, Yang ASP, Lee C, Wu Y, Birkett AJ, Ockenhouse CF, Koelewijn R, van Hellemond JJ, van Genderen PJJ, Sauerwein RW, Prudêncio M. Reuling IJ, et al. Among authors: yang asp. Sci Transl Med. 2020 May 20;12(544):eaay2578. doi: 10.1126/scitranslmed.aay2578. Sci Transl Med. 2020. PMID: 32434846 Clinical Trial.
Generation of Novel Plasmodium falciparum NF135 and NF54 Lines Expressing Fluorescent Reporter Proteins Under the Control of Strong and Constitutive Promoters.
Miyazaki S, Yang ASP, Geurten FJA, Marin-Mogollon C, Miyazaki Y, Imai T, Kolli SK, Ramesar J, Chevalley-Maurel S, Salman AM, van Gemert GA, van Waardenburg YM, Franke-Fayard B, Hill AVS, Sauerwein RW, Janse CJ, Khan SM. Miyazaki S, et al. Among authors: yang asp. Front Cell Infect Microbiol. 2020 Jun 10;10:270. doi: 10.3389/fcimb.2020.00270. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32587831 Free PMC article.
A Potent Anti-Malarial Human Monoclonal Antibody Targets Circumsporozoite Protein Minor Repeats and Neutralizes Sporozoites in the Liver.
Wang LT, Pereira LS, Flores-Garcia Y, O'Connor J, Flynn BJ, Schön A, Hurlburt NK, Dillon M, Yang ASP, Fabra-García A, Idris AH, Mayer BT, Gerber MW, Gottardo R, Mason RD, Cavett N, Ballard RB, Kisalu NK, Molina-Cruz A, Nelson J, Vistein R, Barillas-Mury C, Amino R, Baker D, King NP, Sauerwein RW, Pancera M, Cockburn IA, Zavala F, Francica JR, Seder RA. Wang LT, et al. Among authors: yang asp. Immunity. 2020 Oct 13;53(4):733-744.e8. doi: 10.1016/j.immuni.2020.08.014. Epub 2020 Sep 17. Immunity. 2020. PMID: 32946741 Free PMC article. Clinical Trial.
Systematic Identification of Plasmodium Falciparum Sporozoite Membrane Protein Interactions Reveals an Essential Role for the p24 Complex in Host Infection.
Knöckel J, Dundas K, Yang ASP, Galaway F, Metcalf T, Gemert GV, Sauerwein RW, Rayner JC, Billker O, Wright GJ. Knöckel J, et al. Among authors: yang asp. Mol Cell Proteomics. 2021;20:100038. doi: 10.1074/mcp.RA120.002432. Epub 2021 Jan 27. Mol Cell Proteomics. 2021. PMID: 33515807 Free PMC article.
Novel insights from the Plasmodium falciparum sporozoite-specific proteome by probabilistic integration of 26 studies.
Meerstein-Kessel L, Venhuizen J, Garza D, Proellochs NI, Vos EJ, Obiero JM, Felgner PL, Sauerwein RW, Peters M, Yang ASP, Huynen MA. Meerstein-Kessel L, et al. Among authors: yang asp. PLoS Comput Biol. 2021 Apr 30;17(4):e1008067. doi: 10.1371/journal.pcbi.1008067. eCollection 2021 Apr. PLoS Comput Biol. 2021. PMID: 33930021 Free PMC article.
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