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Targeting alternative splicing as a new cancer immunotherapy-phosphorylation of serine arginine-rich splicing factor (SRSF1) by SR protein kinase 1 (SRPK1) regulates alternative splicing of PD1 to generate a soluble antagonistic isoform that prevents T cell exhaustion.
Wahid M, Pratoomthai B, Egbuniwe IU, Evans HR, Babaei-Jadidi R, Amartey JO, Erdelyi V, Yacqub-Usman K, Jackson AM, Morris JC, Patel PM, Bates DO. Wahid M, et al. Among authors: bates do. Cancer Immunol Immunother. 2023 Dec;72(12):4001-4014. doi: 10.1007/s00262-023-03534-z. Epub 2023 Nov 16. Cancer Immunol Immunother. 2023. PMID: 37973660 Free PMC article.
Measurement of solute permeability in the mouse spinal cord.
Lobo MEDV, Bates DO, Arkill KP, Hulse RP. Lobo MEDV, et al. Among authors: bates do. J Neurosci Methods. 2023 Jun 1;393:109880. doi: 10.1016/j.jneumeth.2023.109880. Epub 2023 May 11. J Neurosci Methods. 2023. PMID: 37178727 Free article.
The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1.
Pruszko M, Milano E, Forcato M, Donzelli S, Ganci F, Di Agostino S, De Panfilis S, Fazi F, Bates DO, Bicciato S, Zylicz M, Zylicz A, Blandino G, Fontemaggi G. Pruszko M, et al. Among authors: bates do. EMBO Rep. 2017 Aug;18(8):1331-1351. doi: 10.15252/embr.201643370. Epub 2017 Jun 26. EMBO Rep. 2017. PMID: 28652379 Free PMC article.
Preclinical evidence for anaplastic lymphoma kinase inhibitors as novel therapeutic treatments for cholangiocarcinoma.
Myint KZ, Sueca-Comes M, Collier P, Balasubramanian B, Venkatraman S, Gordan J, Zaitoun AM, Mukherjee A, Arora A, Larbcharoensub N, Suriyonplengsaeng C, Wongprasert K, Janvilisri T, Gomez D, Grabowska AM, Tohtong R, Bates DO, Yacqub-Usman K. Myint KZ, et al. Among authors: bates do. Front Oncol. 2023 Dec 7;13:1184900. doi: 10.3389/fonc.2023.1184900. eCollection 2023. Front Oncol. 2023. PMID: 38144528 Free PMC article.
Apoptosis in Cancer Cells Is Induced by Alternative Splicing of hnRNPA2/B1 Through Splicing of Bcl-x, a Mechanism that Can Be Stimulated by an Extract of the South African Medicinal Plant, Cotyledon orbiculata.
Makhafola TJ, Mbele M, Yacqub-Usman K, Hendren A, Haigh DB, Blackley Z, Meyer M, Mongan NP, Bates DO, Dlamini Z. Makhafola TJ, et al. Among authors: bates do. Front Oncol. 2020 Oct 8;10:547392. doi: 10.3389/fonc.2020.547392. eCollection 2020. Front Oncol. 2020. PMID: 33163396 Free PMC article.
Therapeutic Implications of Ceritinib in Cholangiocarcinoma beyond ALK Expression and Mutation.
Myint KZ, Balasubramanian B, Venkatraman S, Phimsen S, Sripramote S, Jantra J, Choeiphuk C, Mingphruedhi S, Muangkaew P, Rungsakulkij N, Tangtawee P, Suragul W, Farquharson WV, Wongprasert K, Chutipongtanate S, Sanvarinda P, Ponpuak M, Poungvarin N, Janvilisri T, Suthiphongchai T, Yacqub-Usman K, Grabowska AM, Bates DO, Tohtong R. Myint KZ, et al. Among authors: bates do. Pharmaceuticals (Basel). 2024 Feb 2;17(2):197. doi: 10.3390/ph17020197. Pharmaceuticals (Basel). 2024. PMID: 38399413 Free PMC article.
201 results