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Multicentre randomised controlled trial to investigate usefulness of the rapid diagnostic βLACTA test performed directly on bacterial cell pellets from respiratory, urinary or blood samples for the early de-escalation of carbapenems in septic intensive care unit patients: the BLUE-CarbA protocol.
Garnier M, Gallah S, Vimont S, Benzerara Y, Labbe V, Constant AL, Siami S, Guerot E, Compain F, Mainardi JL, Montil M, Quesnel C; BLUE-CarbA study group.. Garnier M, et al. Among authors: mainardi jl. BMJ Open. 2019 Feb 19;9(2):e024561. doi: 10.1136/bmjopen-2018-024561. BMJ Open. 2019. PMID: 30782909 Free PMC article.
Hydrolysis of clavulanate by Mycobacterium tuberculosis β-lactamase BlaC harboring a canonical SDN motif.
Soroka D, Li de la Sierra-Gallay I, Dubée V, Triboulet S, van Tilbeurgh H, Compain F, Ballell L, Barros D, Mainardi JL, Hugonnet JE, Arthur M. Soroka D, et al. Among authors: mainardi jl. Antimicrob Agents Chemother. 2015 Sep;59(9):5714-20. doi: 10.1128/AAC.00598-15. Epub 2015 Jul 6. Antimicrob Agents Chemother. 2015. PMID: 26149997 Free PMC article.
Routes of Synthesis of Carbapenems for Optimizing Both the Inactivation of L,D-Transpeptidase LdtMt1 of Mycobacterium tuberculosis and the Stability toward Hydrolysis by β-Lactamase BlaC.
Iannazzo L, Soroka D, Triboulet S, Fonvielle M, Compain F, Dubée V, Mainardi JL, Hugonnet JE, Braud E, Arthur M, Etheve-Quelquejeu M. Iannazzo L, et al. Among authors: mainardi jl. J Med Chem. 2016 Apr 14;59(7):3427-38. doi: 10.1021/acs.jmedchem.6b00096. Epub 2016 Mar 18. J Med Chem. 2016. PMID: 26937999
Inhibition of β-lactamases of mycobacteria by avibactam and clavulanate.
Soroka D, Ourghanlian C, Compain F, Fichini M, Dubée V, Mainardi JL, Hugonnet JE, Arthur M. Soroka D, et al. Among authors: mainardi jl. J Antimicrob Chemother. 2017 Apr 1;72(4):1081-1088. doi: 10.1093/jac/dkw546. J Antimicrob Chemother. 2017. PMID: 28039278
Inhibition of the β-Lactamase BlaMab by Avibactam Improves the In Vitro and In Vivo Efficacy of Imipenem against Mycobacterium abscessus.
Lefebvre AL, Le Moigne V, Bernut A, Veckerlé C, Compain F, Herrmann JL, Kremer L, Arthur M, Mainardi JL. Lefebvre AL, et al. Among authors: mainardi jl. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02440-16. doi: 10.1128/AAC.02440-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28096155 Free PMC article.
212 results