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An effective in vitro and in vivo antileishmanial activity and mechanism of action of 8-hydroxyquinoline against Leishmania species causing visceral and tegumentary leishmaniasis.
Costa Duarte M, dos Reis Lage LM, Lage DP, Mesquita JT, Salles BC, Lavorato SN, Menezes-Souza D, Roatt BM, Alves RJ, Tavares CA, Tempone AG, Coelho EA. Costa Duarte M, et al. Among authors: lavorato sn. Vet Parasitol. 2016 Feb 15;217:81-8. doi: 10.1016/j.vetpar.2016.01.002. Epub 2016 Jan 7. Vet Parasitol. 2016. PMID: 26827866
1,3-Bis(aryloxy)propan-2-ols as potential antileishmanial agents.
Lavorato SN, Duarte MC, Lage DP, Tavares CAP, Coelho EAF, Alves RJ. Lavorato SN, et al. Chem Biol Drug Des. 2017 Nov;90(5):981-986. doi: 10.1111/cbdd.13024. Epub 2017 Jun 28. Chem Biol Drug Des. 2017. PMID: 28590516 Free PMC article.
Chloroacetamide derivatives as a promising topical treatment for fungal skin infections.
Machado GDRM, Fernandes de Andrade S, Pippi B, Bergamo VZ, Jacobus Berlitz S, Lopes W, Lavorato SN, Clemes Külkamp Guerreiro I, Vainstein MH, Teixeira ML, Alves RJ, Fuentefria AM. Machado GDRM, et al. Among authors: lavorato sn. Mycologia. 2019 Jul-Aug;111(4):612-623. doi: 10.1080/00275514.2019.1620550. Epub 2019 Jun 17. Mycologia. 2019. PMID: 31204895
Pharmacological and physicochemical profile of arylacetamides as tools against human cancers.
Ferreira PMP, Machado KDC, Lavorato SN, Oliveira FCE, Silva JDN, Almeida AAC, Santos LS, Silva VR, Bezerra DP, Soares MBP, Pessoa C, Moraes Filho MO, Ferreira JRO, Sousa JMCE, Maltarollo VG, Alves RJ. Ferreira PMP, et al. Among authors: lavorato sn. Toxicol Appl Pharmacol. 2019 Oct 1;380:114692. doi: 10.1016/j.taap.2019.114692. Epub 2019 Jul 26. Toxicol Appl Pharmacol. 2019. PMID: 31356931 Free article.
In vitro pharmacokinetics/pharmacodynamics modeling and efficacy against systemic candidiasis in Drosophila melanogaster of a bisaryloxypropanamine derivative.
Dalla Lana DF, Kaminski TFA, Lavorato SN, Merkel S, Zanette RA, da Rosa PD, Staudt KJ, de Araújo BV, da Costa B, Quatrin PM, Bazana LCG, Ferreira FA, Caurio CFB, de Andrade SF, Alves RJ, Fuentefria AM. Dalla Lana DF, et al. Among authors: lavorato sn. Med Mycol. 2021 Jan 4;59(1):58-66. doi: 10.1093/mmy/myaa030. Med Mycol. 2021. PMID: 32407486
Structure-based discovery of thiosemicarbazones as SARS-CoV-2 main protease inhibitors.
Maltarollo VG, da Silva EB, Kronenberger T, Sena Andrade MM, de Lima Marques GV, Cândido Oliveira NJ, Santos LH, Oliveira Rezende Júnior C, Cassiano Martinho AC, Skinner D, Fajtová P, M Fernandes TH, Silveira Dos Santos ED, Rodrigues Gazolla PA, Martins de Souza AP, da Silva ML, Dos Santos FS, Lavorato SN, Oliveira Bretas AC, Carvalho DT, Franco LL, Luedtke S, Giardini MA, Poso A, Dias LC, Podust LM, Alves RJ, McKerrow J, Andrade SF, Teixeira RR, Siqueira-Neto JL, O'Donoghue A, de Oliveira RB, Ferreira RS. Maltarollo VG, et al. Among authors: lavorato sn. Future Med Chem. 2023 Jun;15(11):959-985. doi: 10.4155/fmc-2023-0034. Epub 2023 Jul 12. Future Med Chem. 2023. PMID: 37435731
17 results