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An effective in vitro and in vivo antileishmanial activity and mechanism of action of 8-hydroxyquinoline against Leishmania species causing visceral and tegumentary leishmaniasis.
Costa Duarte M, dos Reis Lage LM, Lage DP, Mesquita JT, Salles BC, Lavorato SN, Menezes-Souza D, Roatt BM, Alves RJ, Tavares CA, Tempone AG, Coelho EA. Costa Duarte M, et al. Among authors: alves rj. Vet Parasitol. 2016 Feb 15;217:81-8. doi: 10.1016/j.vetpar.2016.01.002. Epub 2016 Jan 7. Vet Parasitol. 2016. PMID: 26827866
1,3-Bis(aryloxy)propan-2-ols as potential antileishmanial agents.
Lavorato SN, Duarte MC, Lage DP, Tavares CAP, Coelho EAF, Alves RJ. Lavorato SN, et al. Among authors: alves rj. Chem Biol Drug Des. 2017 Nov;90(5):981-986. doi: 10.1111/cbdd.13024. Epub 2017 Jun 28. Chem Biol Drug Des. 2017. PMID: 28590516 Free PMC article.
Chloroacetamide derivatives as a promising topical treatment for fungal skin infections.
Machado GDRM, Fernandes de Andrade S, Pippi B, Bergamo VZ, Jacobus Berlitz S, Lopes W, Lavorato SN, Clemes Külkamp Guerreiro I, Vainstein MH, Teixeira ML, Alves RJ, Fuentefria AM. Machado GDRM, et al. Among authors: alves rj. Mycologia. 2019 Jul-Aug;111(4):612-623. doi: 10.1080/00275514.2019.1620550. Epub 2019 Jun 17. Mycologia. 2019. PMID: 31204895
Pharmacological and physicochemical profile of arylacetamides as tools against human cancers.
Ferreira PMP, Machado KDC, Lavorato SN, Oliveira FCE, Silva JDN, Almeida AAC, Santos LS, Silva VR, Bezerra DP, Soares MBP, Pessoa C, Moraes Filho MO, Ferreira JRO, Sousa JMCE, Maltarollo VG, Alves RJ. Ferreira PMP, et al. Among authors: alves rj. Toxicol Appl Pharmacol. 2019 Oct 1;380:114692. doi: 10.1016/j.taap.2019.114692. Epub 2019 Jul 26. Toxicol Appl Pharmacol. 2019. PMID: 31356931 Free article.
In vitro pharmacokinetics/pharmacodynamics modeling and efficacy against systemic candidiasis in Drosophila melanogaster of a bisaryloxypropanamine derivative.
Dalla Lana DF, Kaminski TFA, Lavorato SN, Merkel S, Zanette RA, da Rosa PD, Staudt KJ, de Araújo BV, da Costa B, Quatrin PM, Bazana LCG, Ferreira FA, Caurio CFB, de Andrade SF, Alves RJ, Fuentefria AM. Dalla Lana DF, et al. Among authors: alves rj. Med Mycol. 2021 Jan 4;59(1):58-66. doi: 10.1093/mmy/myaa030. Med Mycol. 2021. PMID: 32407486
Do Drug-likeness Rules Apply to Oral Prodrugs?
Protti ÍF, Rodrigues DR, Fonseca SK, Alves RJ, de Oliveira RB, Maltarollo VG. Protti ÍF, et al. Among authors: alves rj. ChemMedChem. 2021 May 6;16(9):1446-1456. doi: 10.1002/cmdc.202000805. Epub 2021 Feb 25. ChemMedChem. 2021. PMID: 33471444
142 results