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Allostery in GPCRs: 'MWC' revisited.
Canals M, Sexton PM, Christopoulos A. Canals M, et al. Trends Biochem Sci. 2011 Dec;36(12):663-72. doi: 10.1016/j.tibs.2011.08.005. Epub 2011 Sep 14. Trends Biochem Sci. 2011. PMID: 21920759 Review.
Regulation of G protein-coupled receptors by allosteric ligands.
Lane JR, Abdul-Ridha A, Canals M. Lane JR, et al. Among authors: canals m. ACS Chem Neurosci. 2013 Apr 17;4(4):527-34. doi: 10.1021/cn400005t. Epub 2013 Feb 21. ACS Chem Neurosci. 2013. PMID: 23398684 Free PMC article. Review.
The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts.
Jensen DD, Godfrey CB, Niklas C, Canals M, Kocan M, Poole DP, Murphy JE, Alemi F, Cottrell GS, Korbmacher C, Lambert NA, Bunnett NW, Corvera CU. Jensen DD, et al. Among authors: canals m. J Biol Chem. 2013 Aug 9;288(32):22942-60. doi: 10.1074/jbc.M113.455774. Epub 2013 Jul 1. J Biol Chem. 2013. PMID: 23818521 Free PMC article.
Agonist-biased trafficking of somatostatin receptor 2A in enteric neurons.
Zhao P, Canals M, Murphy JE, Klingler D, Eriksson EM, Pelayo JC, Hardt M, Bunnett NW, Poole DP. Zhao P, et al. Among authors: canals m. J Biol Chem. 2013 Sep 6;288(36):25689-25700. doi: 10.1074/jbc.M113.496414. Epub 2013 Aug 2. J Biol Chem. 2013. PMID: 23913690 Free PMC article.
308 results