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Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells.
Trapasso F, Pichiorri F, Gaspari M, Palumbo T, Aqeilan RI, Gaudio E, Okumura H, Iuliano R, Di Leva G, Fabbri M, Birk DE, Raso C, Green-Church K, Spagnoli LG, Venuta S, Huebner K, Croce CM. Trapasso F, et al. Among authors: pichiorri f. J Biol Chem. 2008 May 16;283(20):13736-44. doi: 10.1074/jbc.M709062200. Epub 2008 Mar 3. J Biol Chem. 2008. PMID: 18319262 Free PMC article. Retracted.
Fhit tumor suppressor: guardian of the preneoplastic genome.
Pichiorri F, Palumbo T, Suh SS, Okamura H, Trapasso F, Ishii H, Huebner K, Croce CM. Pichiorri F, et al. Future Oncol. 2008 Dec;4(6):815-24. doi: 10.2217/14796694.4.6.815. Future Oncol. 2008. PMID: 19086848 Free PMC article. Review.
140 results