Namour F - Search Results

1

The Relative Bioavailability and Effects of Food and Acid-Reducing Agents on Filgotinib Tablets in Healthy Subjects.

Anderson K, Zheng H, Kotecha M, Cuvin J, Scott B, Sharma S, Qin AR, Namour F, Xin Y. Anderson K, et al. Among authors: namour f. Clin Pharmacol Drug Dev. 2019 Jul;8(5):585-594. doi: 10.1002/cpdd.659. Epub 2019 Feb 15. Clin Pharmacol Drug Dev. 2019. PMID: 30768860 Clinical Trial.

2

Pharmacokinetics, safety, and tolerability of GLPG0259, a mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5) inhibitor, given as single and multiple doses to healthy male subjects.

Namour F, Vanhoutte FP, Beetens J, Blockhuys S, De Weer M, Wigerinck P. Namour F, et al. Drugs R D. 2012 Sep 1;12(3):141-63. doi: 10.2165/11633120-000000000-00000. Drugs R D. 2012. PMID: 22950522 Free PMC article. Clinical Trial.

3

Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Modeling of Filgotinib (GLPG0634), a Selective JAK1 Inhibitor, in Support of Phase IIB Dose Selection.

Namour F, Diderichsen PM, Cox E, Vayssière B, Van der Aa A, Tasset C, Van't Klooster G. Namour F, et al. Clin Pharmacokinet. 2015 Aug;54(8):859-74. doi: 10.1007/s40262-015-0240-z. Clin Pharmacokinet. 2015. PMID: 25681059 Free PMC article. Clinical Trial.

4

Clinical Confirmation that the Selective JAK1 Inhibitor Filgotinib (GLPG0634) has a Low Liability for Drug-drug Interactions.

Namour F, Desrivot J, Van der Aa A, Harrison P, Tasset C, van't Klooster G. Namour F, et al. Drug Metab Lett. 2016;10(1):38-48. doi: 10.2174/1872312810666151223103353. Drug Metab Lett. 2016. PMID: 26693854 Clinical Trial.

5

Safety, pharmacokinetics and pharmacodynamics of GLPG0974, a potent and selective FFA2 antagonist, in healthy male subjects.

Namour F, Galien R, Van Kaem T, Van der Aa A, Vanhoutte F, Beetens J, Van't Klooster G. Namour F, et al. Br J Clin Pharmacol. 2016 Jul;82(1):139-48. doi: 10.1111/bcp.12900. Epub 2016 May 1. Br J Clin Pharmacol. 2016. PMID: 26852904 Free PMC article. Clinical Trial.

6

Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Filgotinib, a Selective JAK-1 Inhibitor, After Short-Term Treatment of Rheumatoid Arthritis: Results of Two Randomized Phase IIa Trials.

Vanhoutte F, Mazur M, Voloshyn O, Stanislavchuk M, Van der Aa A, Namour F, Galien R, Meuleners L, van 't Klooster G. Vanhoutte F, et al. Among authors: namour f. Arthritis Rheumatol. 2017 Oct;69(10):1949-1959. doi: 10.1002/art.40186. Epub 2017 Aug 31. Arthritis Rheumatol. 2017. PMID: 28622463 Free PMC article. Clinical Trial.

7

Influence of age and renal impairment on the steady state pharmacokinetics of filgotinib, a selective JAK1 inhibitor.

Namour F, Fagard L, Van der Aa A, Harrison P, Xin Y, Tasset C. Namour F, et al. Br J Clin Pharmacol. 2018 Dec;84(12):2779-2789. doi: 10.1111/bcp.13726. Epub 2018 Oct 4. Br J Clin Pharmacol. 2018. PMID: 30088677 Free PMC article.

8

Filgotinib, a JAK1 Inhibitor, Has No Effect on QT Interval in Healthy Subjects.

Anderson K, Xin Y, Zheng H, Yun C, Kwan E, Qin A, Namour F, Kearney BP, Mathias A. Anderson K, et al. Among authors: namour f. Clin Pharmacol Drug Dev. 2020 Jan;9(1):32-40. doi: 10.1002/cpdd.755. Epub 2019 Dec 2. Clin Pharmacol Drug Dev. 2020. PMID: 31797578 Clinical Trial.

9

Filgotinib: A Clinical Pharmacology Review.

Namour F, Anderson K, Nelson C, Tasset C. Namour F, et al. Clin Pharmacokinet. 2022 Jun;61(6):819-832. doi: 10.1007/s40262-022-01129-y. Epub 2022 May 31. Clin Pharmacokinet. 2022. PMID: 35637376 Free PMC article. Review.

10

Ziritaxestat Drug-Drug Interaction with Oral Contraceptives: Role of SULT1E1 Inhibition.

Helmer E, Karimian N, Van Assche K, Seghers I, Le Tallec S, Cherala G, Scott G, Namour FS. Helmer E, et al. Among authors: namour fs. Clin Pharmacol Ther. 2022 Oct;112(4):901-908. doi: 10.1002/cpt.2689. Epub 2022 Jul 12. Clin Pharmacol Ther. 2022. PMID: 35713964 Free PMC article.

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