De Grandis RA - Search Results

1

Acid diterpenes from Copaiba oleoresin (Copaifera langsdorffii): Chemical and plasma stability and intestinal permeability using Caco-2 cells.

Mauro M, De Grandis RA, Campos ML, Bauermeister A, Peccinini RG, Pavan FR, Lopes NP, De Moraes NV. Mauro M, et al. Among authors: de grandis ra, de moraes nv. J Ethnopharmacol. 2019 May 10;235:183-189. doi: 10.1016/j.jep.2019.02.017. Epub 2019 Feb 11. J Ethnopharmacol. 2019. PMID: 30763698 Free article.

2

In vitro evaluation of the cyto-genotoxic potential of Ruthenium(II) SCAR complexes: a promising class of antituberculosis agents.

De Grandis RA, Resende FA, da Silva MM, Pavan FR, Batista AA, Varanda EA. De Grandis RA, et al. Mutat Res Genet Toxicol Environ Mutagen. 2016 Mar;798-799:11-8. doi: 10.1016/j.mrgentox.2016.01.007. Epub 2016 Feb 1. Mutat Res Genet Toxicol Environ Mutagen. 2016. PMID: 26994489

3

Human topoisomerase inhibition and DNA/BSA binding of Ru(II)-SCAR complexes as potential anticancer candidates for oral application.

De Grandis RA, de Camargo MS, da Silva MM, Lopes ÉO, Padilha EC, Resende FA, Peccinini RG, Pavan FR, Desideri A, Batista AA, Varanda EA. De Grandis RA, et al. Among authors: de camargo ms. Biometals. 2017 Jun;30(3):321-334. doi: 10.1007/s10534-017-0008-z. Epub 2017 Mar 16. Biometals. 2017. PMID: 28303361

4

Determination of in vitro absorption in Caco-2 monolayers of anticancer Ru(II)-based complexes acting as dual human topoisomerase and PARP inhibitors.

de Camargo MS, De Grandis RA, da Silva MM, da Silva PB, Santoni MM, Eismann CE, Menegário AA, Cominetti MR, Zanelli CF, Pavan FR, Batista AA. de Camargo MS, et al. Among authors: de grandis ra. Biometals. 2019 Feb;32(1):89-100. doi: 10.1007/s10534-018-0160-0. Epub 2018 Nov 30. Biometals. 2019. PMID: 30506342

5

Novel lawsone-containing ruthenium(II) complexes: Synthesis, characterization and anticancer activity on 2D and 3D spheroid models of prostate cancer cells.

De Grandis RA, Santos PWDSD, Oliveira KM, Machado ART, Aissa AF, Batista AA, Antunes LMG, Pavan FR. De Grandis RA, et al. Bioorg Chem. 2019 Apr;85:455-468. doi: 10.1016/j.bioorg.2019.02.010. Epub 2019 Feb 8. Bioorg Chem. 2019. PMID: 30776556

6

Cyto-genotoxic evaluation of novel anti-tubercular copper (II) complexes containing isoniazid-based ligands.

Fregonezi NF, Aparecida de Souza F, Aleixo NA, Stefany da Silva Gomes P, Silvestre RB, De Grandis RA, Bento da Silva P, Pavan FR, Chorilli M, Resende FA. Fregonezi NF, et al. Among authors: de grandis ra. Regul Toxicol Pharmacol. 2020 Jun;113:104653. doi: 10.1016/j.yrtph.2020.104653. Epub 2020 Apr 5. Regul Toxicol Pharmacol. 2020. PMID: 32268159

7

Furoxan derivatives demonstrated in vivo efficacy by reducing Mycobacterium tuberculosis to undetectable levels in a mouse model of infection.

de Souza PC, Fernandes GFS, Marino LB, Ribeiro CM, Silva PBD, Chorilli M, Silva CSP, Resende FA, Solcia MC, de Grandis RA, Costa CAS, Cho SH, Wang Y, Franzblau SG, Dos Santos JL, Pavan FR. de Souza PC, et al. Among authors: de grandis ra. Biomed Pharmacother. 2020 Oct;130:110592. doi: 10.1016/j.biopha.2020.110592. Epub 2020 Aug 4. Biomed Pharmacother. 2020. PMID: 32763822 Free article.

8

Assessment of the Physicochemical Properties and Stability for Pharmacokinetic Prediction of Pyrazinoic Acid Derivatives.

Franchin TB, Ulian Silva BC, DeGrandis RA, Corrêa MF, de Queiroz Aranha CMS, Fernandes JPS, Campos ML, Peccinini RG. Franchin TB, et al. Curr Drug Metab. 2020;21(9):714-721. doi: 10.2174/1389200221666200907145722. Curr Drug Metab. 2020. PMID: 32895039

9

Hydroalcoholic Extract of Myrcia bella Loaded into a Microemulsion System: A Study of Antifungal and Mutagenic Potential.

Marena GD, Girotto L, Saldanha LL, Ramos MADS, De Grandis RA, da Silva PB, Dokkedal AL, Chorilli M, Bauab TM, Pavan FR, Trovatti E, Lustri WR, Resende FA. Marena GD, et al. Among authors: de grandis ra. Planta Med. 2022 Apr;88(5):405-415. doi: 10.1055/a-1323-3622. Epub 2021 Jan 28. Planta Med. 2022. PMID: 33511621

10

A Novel Ruthenium(II) Complex With Lapachol Induces G2/M Phase Arrest Through Aurora-B Kinase Down-Regulation and ROS-Mediated Apoptosis in Human Prostate Adenocarcinoma Cells.

De Grandis RA, Oliveira KM, Guedes APM, Dos Santos PWS, Aissa AF, Batista AA, Pavan FR. De Grandis RA, et al. Front Oncol. 2021 Jun 24;11:682968. doi: 10.3389/fonc.2021.682968. eCollection 2021. Front Oncol. 2021. PMID: 34249731 Free PMC article.

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