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Destabilization of AETFC through C/EBPα-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation.
Zhang MM, Liu N, Zhang YL, Rong B, Wang XL, Xu CH, Xie YY, Shen S, Zhu J, Nimer SD, Chen Z, Chen SJ, Roeder RG, Lan F, Wang L, Huang QH, Sun XJ. Zhang MM, et al. Among authors: wang l, wang xl. Leukemia. 2019 Jul;33(7):1822-1827. doi: 10.1038/s41375-019-0398-8. Epub 2019 Feb 12. Leukemia. 2019. PMID: 30755707 Free PMC article. No abstract available.
Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis.
Liu N, Song J, Xie Y, Wang XL, Rong B, Man N, Zhang MM, Zhang Q, Gao FF, Du MR, Zhang Y, Shen J, Xu CH, Hu CL, Wu JC, Liu P, Zhang YL, Xie YY, Liu P, Huang JY, Huang QH, Lan F, Shen S, Nimer SD, Chen Z, Chen SJ, Roeder RG, Wang L, Sun XJ. Liu N, et al. Among authors: wang l, wang xl. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):890-899. doi: 10.1073/pnas.1809327116. Epub 2018 Dec 28. Proc Natl Acad Sci U S A. 2019. PMID: 30593567 Free PMC article.
A direct comparison between AML1-ETO and ETO2-GLIS2 leukemia fusion proteins reveals context-dependent binding and regulation of target genes and opposite functions in cell differentiation.
Zhang YF, Wang XL, Xu CH, Liu N, Zhang L, Zhang YM, Xie YY, Zhang YL, Huang QH, Wang L, Chen Z, Chen SJ, Roeder RG, Shen S, Xue K, Sun XJ. Zhang YF, et al. Among authors: wang l, wang xl. Front Cell Dev Biol. 2022 Sep 7;10:992714. doi: 10.3389/fcell.2022.992714. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36158200 Free PMC article.
4,082 results