Neuromedin U is a gut peptide that alters oral glucose tolerance by delaying gastric emptying via direct contraction of the pylorus and vagal-dependent mechanisms.
Jarry AC, Merah N, Cisse F, Cayetanot F, Fiamma MN, Willemetz A, Gueddouri D, Barka B, Valet P, Guilmeau S, Bado A, Le Beyec J, Bodineau L, Le Gall M.
Jarry AC, et al. Among authors: bado a.
FASEB J. 2019 Apr;33(4):5377-5388. doi: 10.1096/fj.201801718R. Epub 2019 Feb 12.
FASEB J. 2019.
PMID: 30753087
NMU receptors 1 and 2 were detected in pyloric muscles and NMU was able to directly induce pyloric contraction in a dose-dependent manner ex vivo in isometric chambers. Using a modified glucose tolerance test, we demonstrate that improvement of oral glucose toleranc …
NMU receptors 1 and 2 were detected in pyloric muscles and NMU was able to directly induce pyloric contraction in a dose-dependent ma …