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Next-Generation Cell-Active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase.
Lazo JS, Blanco IK, Tasker NR, Rastelli EJ, Burnett JC, Garrott SR, Hart DJ, McCloud RL, Hsu KL, Wipf P, Sharlow ER. Lazo JS, et al. Among authors: burnett jc. J Pharmacol Exp Ther. 2019 Dec;371(3):652-662. doi: 10.1124/jpet.119.262188. Epub 2019 Oct 10. J Pharmacol Exp Ther. 2019. PMID: 31601683 Free PMC article.
Small molecule targeting of PTPs in cancer.
Lazo JS, McQueeney KE, Burnett JC, Wipf P, Sharlow ER. Lazo JS, et al. Among authors: burnett jc. Int J Biochem Cell Biol. 2018 Mar;96:171-181. doi: 10.1016/j.biocel.2017.09.011. Epub 2017 Sep 21. Int J Biochem Cell Biol. 2018. PMID: 28943273 Review.
Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor.
McQueeney KE, Salamoun JM, Burnett JC, Barabutis N, Pekic P, Lewandowski SL, Llaneza DC, Cornelison R, Bai Y, Zhang ZY, Catravas JD, Landen CN, Wipf P, Lazo JS, Sharlow ER. McQueeney KE, et al. Among authors: burnett jc. Oncotarget. 2017 Dec 30;9(9):8223-8240. doi: 10.18632/oncotarget.23787. eCollection 2018 Feb 2. Oncotarget. 2017. PMID: 29492190 Free PMC article.
Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
Burnett JC, Ruthel G, Stegmann CM, Panchal RG, Nguyen TL, Hermone AR, Stafford RG, Lane DJ, Kenny TA, McGrath CF, Wipf P, Stahl AM, Schmidt JJ, Gussio R, Brunger AT, Bavari S. Burnett JC, et al. J Biol Chem. 2007 Feb 16;282(7):5004-5014. doi: 10.1074/jbc.M608166200. Epub 2006 Nov 8. J Biol Chem. 2007. PMID: 17092934 Free article.
Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97.
LaPorte MG, Burnett JC, Colombo R, Bulfer SL, Alverez C, Chou TF, Neitz RJ, Green N, Moore WJ, Yue Z, Li S, Arkin MR, Wipf P, Huryn DM. LaPorte MG, et al. Among authors: burnett jc. ACS Med Chem Lett. 2018 Sep 18;9(11):1075-1081. doi: 10.1021/acsmedchemlett.8b00372. eCollection 2018 Nov 8. ACS Med Chem Lett. 2018. PMID: 30429948 Free PMC article.
639 results