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Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in Vivo.
White BH, Whalen K, Kriksciukaite K, Alargova R, Au Yeung T, Bazinet P, Brockman A, DuPont M, Oller H, Lemelin CA, Lim Soo P, Moreau B, Perino S, Quinn JM, Sharma G, Shinde R, Sweryda-Krawiec B, Wooster R, Bilodeau MT. White BH, et al. J Med Chem. 2019 Mar 14;62(5):2708-2719. doi: 10.1021/acs.jmedchem.8b02036. Epub 2019 Feb 28. J Med Chem. 2019. PMID: 30735385
Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer.
Whalen KA, White BH, Quinn JM, Kriksciukaite K, Alargova R, Au Yeung TP, Bazinet P, Brockman A, DuPont MM, Oller H, Gifford J, Lemelin CA, Lim Soo P, Perino S, Moreau B, Sharma G, Shinde R, Sweryda-Krawiec B, Bilodeau MT, Wooster R. Whalen KA, et al. Among authors: white bh. Mol Cancer Ther. 2019 Nov;18(11):1926-1936. doi: 10.1158/1535-7163.MCT-19-0022. Mol Cancer Ther. 2019. PMID: 31649014
Novel Miniaturized Drug Conjugate Leverages HSP90-driven Tumor Accumulation to Overcome PI3K Inhibitor Delivery Challenges to Solid Tumors.
Perino S, Moreau B, Freda J, Cirello A, White BH, Quinn JM, Kriksciukaite K, Someshwar A, Romagnoli J, Robinson M, Movassaghian S, Cipriani T, Wooster R, Bilodeau MT, Whalen KA. Perino S, et al. Among authors: white bh. Mol Cancer Ther. 2020 Aug;19(8):1613-1622. doi: 10.1158/1535-7163.MCT-19-0964. Epub 2020 Jun 4. Mol Cancer Ther. 2020. PMID: 32499300
Hox gene-specific cellular targeting using split intein Trojan exons.
Diao F, Vasudevan D, Heckscher ES, White BH. Diao F, et al. Among authors: white bh. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2317083121. doi: 10.1073/pnas.2317083121. Epub 2024 Apr 11. Proc Natl Acad Sci U S A. 2024. PMID: 38602904 Free PMC article.
Author Correction: Enteric neurons increase maternal food intake during reproduction.
Hadjieconomou D, King G, Gaspar P, Mineo A, Blackie L, Ameku T, Studd C, de Mendoza A, Diao F, White BH, Brown AEX, Plaçais PY, Préat T, Miguel-Aliaga I. Hadjieconomou D, et al. Among authors: white bh. Nature. 2020 Dec;588(7839):E36. doi: 10.1038/s41586-020-3013-2. Nature. 2020. PMID: 33303962 No abstract available.
The Drosophila Split Gal4 System for Neural Circuit Mapping.
Luan H, Diao F, Scott RL, White BH. Luan H, et al. Among authors: white bh. Front Neural Circuits. 2020 Nov 9;14:603397. doi: 10.3389/fncir.2020.603397. eCollection 2020. Front Neural Circuits. 2020. PMID: 33240047 Free PMC article. Review.
89 results