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Discovery of an SSTR2-Targeting Maytansinoid Conjugate (PEN-221) with Potent Activity in Vitro and in Vivo.
J Med Chem. 2019 Mar 14;62(5):2708-2719. doi: 10.1021/acs.jmedchem.8b02036. Epub 2019 Feb 28.
J Med Chem. 2019.
PMID: 30735385
Targeting the Somatostatin Receptor 2 with the Miniaturized Drug Conjugate, PEN-221: A Potent and Novel Therapeutic for the Treatment of Small Cell Lung Cancer.
Whalen KA, White BH, Quinn JM, Kriksciukaite K, Alargova R, Au Yeung TP, Bazinet P, Brockman A, DuPont MM, Oller H, Gifford J, Lemelin CA, Lim Soo P, Perino S, Moreau B, Sharma G, Shinde R, Sweryda-Krawiec B, Bilodeau MT, Wooster R.
Whalen KA, et al. Among authors: lim soo p.
Mol Cancer Ther. 2019 Nov;18(11):1926-1936. doi: 10.1158/1535-7163.MCT-19-0022.
Mol Cancer Ther. 2019.
PMID: 31649014
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Tumor Selective Silencing Using an RNAi-Conjugated Polymeric Nanopharmaceutical.
Svenson S, Case RI, Cole RO, Hwang J, Kabir SR, Lazarus D, Lim Soo P, Ng PS, Peters C, Shum P, Sweryda-Krawiec B, Tripathi S, van der Poll D, Eliasof S.
Svenson S, et al. Among authors: lim soo p.
Mol Pharm. 2016 Mar 7;13(3):737-47. doi: 10.1021/acs.molpharmaceut.5b00608. Epub 2016 Feb 2.
Mol Pharm. 2016.
PMID: 26835715
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Polycaprolactone-block-poly(ethylene oxide) micelles: a nanodelivery system for 17beta-estradiol.
Lim Soo P, Lovric J, Davidson P, Maysinger D, Eisenberg A.
Lim Soo P, et al.
Mol Pharm. 2005 Nov-Dec;2(6):519-27. doi: 10.1021/mp050049h.
Mol Pharm. 2005.
PMID: 16323959
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Drug release mechanism of paclitaxel from a chitosan-lipid implant system: effect of swelling, degradation and morphology.
Lim Soo P, Cho J, Grant J, Ho E, Piquette-Miller M, Allen C.
Lim Soo P, et al.
Eur J Pharm Biopharm. 2008 May;69(1):149-57. doi: 10.1016/j.ejpb.2007.11.003. Epub 2007 Nov 17.
Eur J Pharm Biopharm. 2008.
PMID: 18164931
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