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Therapeutic targeting of HER2-CB2R heteromers in HER2-positive breast cancer.
Blasco-Benito S, Moreno E, Seijo-Vila M, Tundidor I, Andradas C, Caffarel MM, Caro-Villalobos M, Urigüen L, Diez-Alarcia R, Moreno-Bueno G, Hernández L, Manso L, Homar-Ruano P, McCormick PJ, Bibic L, Bernadó-Morales C, Arribas J, Canals M, Casadó V, Canela EI, Guzmán M, Pérez-Gómez E, Sánchez C. Blasco-Benito S, et al. Among authors: canals m. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3863-3872. doi: 10.1073/pnas.1815034116. Epub 2019 Feb 7. Proc Natl Acad Sci U S A. 2019. PMID: 30733293 Free PMC article.
Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers.
Ciruela F, Casadó V, Rodrigues RJ, Luján R, Burgueño J, Canals M, Borycz J, Rebola N, Goldberg SR, Mallol J, Cortés A, Canela EI, López-Giménez JF, Milligan G, Lluis C, Cunha RA, Ferré S, Franco R. Ciruela F, et al. Among authors: canals m. J Neurosci. 2006 Feb 15;26(7):2080-7. doi: 10.1523/JNEUROSCI.3574-05.2006. J Neurosci. 2006. PMID: 16481441 Free PMC article.
Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope-epitope electrostatic interactions between adenosine A2A and dopamine D2 receptors.
Ciruela F, Burgueño J, Casadó V, Canals M, Marcellino D, Goldberg SR, Bader M, Fuxe K, Agnati LF, Lluis C, Franco R, Ferré S, Woods AS. Ciruela F, et al. Among authors: canals m. Anal Chem. 2004 Sep 15;76(18):5354-63. doi: 10.1021/ac049295f. Anal Chem. 2004. PMID: 15362892
Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain.
Jimenez-Vargas NN, Gong J, Wisdom MJ, Jensen DD, Latorre R, Hegron A, Teng S, DiCello JJ, Rajasekhar P, Veldhuis NA, Carbone SE, Yu Y, Lopez-Lopez C, Jaramillo-Polanco J, Canals M, Reed DE, Lomax AE, Schmidt BL, Leong KW, Vanner SJ, Halls ML, Bunnett NW, Poole DP. Jimenez-Vargas NN, et al. Among authors: canals m. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15281-15292. doi: 10.1073/pnas.2000500117. Epub 2020 Jun 16. Proc Natl Acad Sci U S A. 2020. PMID: 32546520 Free PMC article.
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission.
Yarwood RE, Imlach WL, Lieu T, Veldhuis NA, Jensen DD, Klein Herenbrink C, Aurelio L, Cai Z, Christie MJ, Poole DP, Porter CJH, McLean P, Hicks GA, Geppetti P, Halls ML, Canals M, Bunnett NW. Yarwood RE, et al. Among authors: canals m. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12309-12314. doi: 10.1073/pnas.1706656114. Epub 2017 Oct 30. Proc Natl Acad Sci U S A. 2017. PMID: 29087309 Free PMC article.
A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor.
Dekan Z, Sianati S, Yousuf A, Sutcliffe KJ, Gillis A, Mallet C, Singh P, Jin AH, Wang AM, Mohammadi SA, Stewart M, Ratnayake R, Fontaine F, Lacey E, Piggott AM, Du YP, Canals M, Sessions RB, Kelly E, Capon RJ, Alewood PF, Christie MJ. Dekan Z, et al. Among authors: canals m. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22353-22358. doi: 10.1073/pnas.1908662116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611414 Free PMC article.
Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors.
Hillion J, Canals M, Torvinen M, Casado V, Scott R, Terasmaa A, Hansson A, Watson S, Olah ME, Mallol J, Canela EI, Zoli M, Agnati LF, Ibanez CF, Lluis C, Franco R, Ferre S, Fuxe K. Hillion J, et al. Among authors: canals m. J Biol Chem. 2002 May 17;277(20):18091-7. doi: 10.1074/jbc.M107731200. Epub 2002 Feb 28. J Biol Chem. 2002. PMID: 11872740 Free article.
308 results