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Loss of TET proteins in regulatory T cells promotes abnormal proliferation, Foxp3 destabilization and IL-17 expression.
Nakatsukasa H, Oda M, Yin J, Chikuma S, Ito M, Koga-Iizuka M, Someya K, Kitagawa Y, Ohkura N, Sakaguchi S, Koya I, Sanosaka T, Kohyama J, Tsukada YI, Yamanaka S, Takamura-Enya T, Lu Q, Yoshimura A. Nakatsukasa H, et al. Among authors: yoshimura a. Int Immunol. 2019 Apr 26;31(5):335-347. doi: 10.1093/intimm/dxz008. Int Immunol. 2019. PMID: 30726915
Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads.
Tanaka K, Ichiyama K, Hashimoto M, Yoshida H, Takimoto T, Takaesu G, Torisu T, Hanada T, Yasukawa H, Fukuyama S, Inoue H, Nakanishi Y, Kobayashi T, Yoshimura A. Tanaka K, et al. Among authors: yoshimura a. J Immunol. 2008 Mar 15;180(6):3746-56. doi: 10.4049/jimmunol.180.6.3746. J Immunol. 2008. PMID: 18322180
1,493 results