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The Competing Mechanisms of Phosphate Monoester Dianion Hydrolysis.
Duarte F, Barrozo A, Åqvist J, Williams NH, Kamerlin SC. Duarte F, et al. Among authors: kamerlin sc. J Am Chem Soc. 2016 Aug 24;138(33):10664-73. doi: 10.1021/jacs.6b06277. Epub 2016 Aug 15. J Am Chem Soc. 2016. PMID: 27471914 Free PMC article.
Cooperativity and flexibility in enzyme evolution.
Pabis A, Risso VA, Sanchez-Ruiz JM, Kamerlin SC. Pabis A, et al. Among authors: kamerlin sc. Curr Opin Struct Biol. 2018 Feb;48:83-92. doi: 10.1016/j.sbi.2017.10.020. Epub 2017 Nov 12. Curr Opin Struct Biol. 2018. PMID: 29141202 Free article. Review.
Evolution of chalcone isomerase from a noncatalytic ancestor.
Kaltenbach M, Burke JR, Dindo M, Pabis A, Munsberg FS, Rabin A, Kamerlin SCL, Noel JP, Tawfik DS. Kaltenbach M, et al. Nat Chem Biol. 2018 Jun;14(6):548-555. doi: 10.1038/s41589-018-0042-3. Epub 2018 Apr 23. Nat Chem Biol. 2018. PMID: 29686356
The evolution of multiple active site configurations in a designed enzyme.
Hong NS, Petrović D, Lee R, Gryn'ova G, Purg M, Saunders J, Bauer P, Carr PD, Lin CY, Mabbitt PD, Zhang W, Altamore T, Easton C, Coote ML, Kamerlin SCL, Jackson CJ. Hong NS, et al. Nat Commun. 2018 Sep 25;9(1):3900. doi: 10.1038/s41467-018-06305-y. Nat Commun. 2018. PMID: 30254369 Free PMC article.
148 results