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A class of highly selective inhibitors bind to an active state of PI3Kγ.
Nat Chem Biol. 2019 Apr;15(4):348-357. doi: 10.1038/s41589-018-0215-0. Epub 2019 Feb 4.
Nat Chem Biol. 2019.
PMID: 30718815
Backbone 1H, 13C, and 15N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant.
Köhler C, Carlström G, Tångefjord S, Papavoine T, Lepistö M, Edman K, Akke M.
Köhler C, et al. Among authors: papavoine t.
Biomol NMR Assign. 2018 Oct;12(2):263-268. doi: 10.1007/s12104-018-9820-9. Epub 2018 Apr 17.
Biomol NMR Assign. 2018.
PMID: 29667121
Free PMC article.
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Dynamic allosteric communication pathway directing differential activation of the glucocorticoid receptor.
Köhler C, Carlström G, Gunnarsson A, Weininger U, Tångefjord S, Ullah V, Lepistö M, Karlsson U, Papavoine T, Edman K, Akke M.
Köhler C, et al. Among authors: papavoine t.
Sci Adv. 2020 Jul 17;6(29):eabb5277. doi: 10.1126/sciadv.abb5277. eCollection 2020 Jul.
Sci Adv. 2020.
PMID: 32832645
Free PMC article.
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