Wu Y - Search Results

1

Toolbox of Diverse Linkers for Navigating the Cellular Efficacy Landscape of Stapled Peptides.

Wu Y, Kaur A, Fowler E, Wiedmann MM, Young R, Galloway WRJD, Olsen L, Sore HF, Chattopadhyay A, Kwan TT, Xu W, Walsh SJ, de Andrade P, Janecek M, Arumugam S, Itzhaki LS, Lau YH, Spring DR. Wu Y, et al. ACS Chem Biol. 2019 Mar 15;14(3):526-533. doi: 10.1021/acschembio.9b00063. Epub 2019 Feb 7. ACS Chem Biol. 2019. PMID: 30702850

2

Double Strain-Promoted Macrocyclization for the Rapid Selection of Cell-Active Stapled Peptides.

Lau YH, Wu Y, Rossmann M, Tan BX, de Andrade P, Tan YS, Verma C, McKenzie GJ, Venkitaraman AR, Hyvönen M, Spring DR. Lau YH, et al. Among authors: wu y. Angew Chem Int Ed Engl. 2015 Dec 14;54(51):15410-3. doi: 10.1002/anie.201508416. Epub 2015 Nov 2. Angew Chem Int Ed Engl. 2015. PMID: 26768531 Free PMC article.

3

Development of a Multifunctional Benzophenone Linker for Peptide Stapling and Photoaffinity Labelling.

Wu Y, Olsen LB, Lau YH, Jensen CH, Rossmann M, Baker YR, Sore HF, Collins S, Spring DR. Wu Y, et al. Chembiochem. 2016 Apr 15;17(8):689-92. doi: 10.1002/cbic.201500648. Epub 2016 Mar 16. Chembiochem. 2016. PMID: 26919579 Free PMC article.

4

Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides.

Charoenpattarapreeda J, Tan YS, Iegre J, Walsh SJ, Fowler E, Eapen RS, Wu Y, Sore HF, Verma CS, Itzhaki L, Spring DR. Charoenpattarapreeda J, et al. Among authors: wu y. Chem Commun (Camb). 2019 Jul 14;55(55):7914-7917. doi: 10.1039/c9cc04022f. Epub 2019 Jun 21. Chem Commun (Camb). 2019. PMID: 31225847

5

Water-soluble, stable and azide-reactive strained dialkynes for biocompatible double strain-promoted click chemistry.

Sharma K, Strizhak AV, Fowler E, Wang X, Xu W, Hatt Jensen C, Wu Y, Sore HF, Lau YH, Hyvönen M, Itzhaki LS, Spring DR. Sharma K, et al. Among authors: wu y. Org Biomol Chem. 2019 Aug 28;17(34):8014-8018. doi: 10.1039/c9ob01745c. Org Biomol Chem. 2019. PMID: 31418442

6

Peptide stapling techniques based on different macrocyclisation chemistries.

Lau YH, de Andrade P, Wu Y, Spring DR. Lau YH, et al. Among authors: wu y. Chem Soc Rev. 2015 Jan 7;44(1):91-102. doi: 10.1039/c4cs00246f. Epub 2014 Sep 8. Chem Soc Rev. 2015. PMID: 25199043 Review.

7

A two-component 'double-click' approach to peptide stapling.

Lau YH, Wu Y, de Andrade P, Galloway WR, Spring DR. Lau YH, et al. Among authors: wu y. Nat Protoc. 2015 Apr;10(4):585-94. doi: 10.1038/nprot.2015.033. Epub 2015 Mar 12. Nat Protoc. 2015. PMID: 25763835

8

Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein-Protein Interaction in Ovarian Cancer.

Wiedmann MM, Tan YS, Wu Y, Aibara S, Xu W, Sore HF, Verma CS, Itzhaki L, Stewart M, Brenton JD, Spring DR. Wiedmann MM, et al. Among authors: wu y. Angew Chem Int Ed Engl. 2017 Jan 9;56(2):524-529. doi: 10.1002/anie.201609427. Epub 2016 Dec 5. Angew Chem Int Ed Engl. 2017. PMID: 27918136 Free PMC article.

9

Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design.

Wu Y, Villa F, Maman J, Lau YH, Dobnikar L, Simon AC, Labib K, Spring DR, Pellegrini L. Wu Y, et al. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):12866-12872. doi: 10.1002/anie.201705611. Epub 2017 Sep 7. Angew Chem Int Ed Engl. 2017. PMID: 28815832

10

Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst.

Kwan TT, Boutureira O, Frye EC, Walsh SJ, Gupta MK, Wallace S, Wu Y, Zhang F, Sore HF, Galloway WRJD, Chin JW, Welch M, Bernardes GJL, Spring DR. Kwan TT, et al. Among authors: wu y. Chem Sci. 2017 May 1;8(5):3871-3878. doi: 10.1039/c6sc05313k. Epub 2017 Mar 14. Chem Sci. 2017. PMID: 28966779 Free PMC article.

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