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2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action.
Bestgen B, Kufareva I, Seetoh W, Abell C, Hartmann RW, Abagyan R, Le Borgne M, Filhol O, Cochet C, Lomberget T, Engel M. Bestgen B, et al. Among authors: seetoh w. J Med Chem. 2019 Feb 28;62(4):1817-1836. doi: 10.1021/acs.jmedchem.8b01765. Epub 2019 Feb 13. J Med Chem. 2019. PMID: 30689946 Free PMC article.
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site.
Bestgen B, Krimm I, Kufareva I, Kamal AAM, Seetoh WG, Abell C, Hartmann RW, Abagyan R, Cochet C, Le Borgne M, Engel M, Lomberget T. Bestgen B, et al. Among authors: seetoh wg. J Med Chem. 2019 Feb 28;62(4):1803-1816. doi: 10.1021/acs.jmedchem.8b01766. Epub 2019 Feb 18. J Med Chem. 2019. PMID: 30689953 Free PMC article.
Structural insights into the EthR-DNA interaction using native mass spectrometry.
Shiu-Hin Chan D, Seetoh WG, McConnell BN, Matak-Vinković D, Thomas SE, Mendes V, Blaszczyk M, Coyne AG, Blundell TL, Abell C. Shiu-Hin Chan D, et al. Among authors: seetoh wg. Chem Commun (Camb). 2017 Mar 23;53(25):3527-3530. doi: 10.1039/c7cc00804j. Chem Commun (Camb). 2017. PMID: 28287239 Free PMC article.
Application of Fragment-Based Drug Discovery against DNA Gyrase B.
Chen GY, Ng FM, Tan YW, Poulsen A, Seetoh W, Lin G, Kang C, Then SW, Ahmad NH, Wong YL, Ng HQ, Chia CSB, Lau QY, Hill J, Hung AW, Keller TH. Chen GY, et al. Among authors: seetoh w. Chempluschem. 2015 Aug;80(8):1250-1254. doi: 10.1002/cplu.201500197. Epub 2015 Jun 24. Chempluschem. 2015. PMID: 31973307
Mono-2-ethylhexylphthalate (MEHP) is a potent agonist of human TRPA1 channel.
Goh M, Fu L, Seetoh WG, Koay A, Hua H, Tan SM, Tay SH, Jinfeng EC, Abdullah N, Ng SY, Lakshmanan M, Arumugam P. Goh M, et al. Among authors: seetoh wg. Chemosphere. 2024 Feb;349:140740. doi: 10.1016/j.chemosphere.2023.140740. Epub 2023 Nov 23. Chemosphere. 2024. PMID: 38006918
15 results