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In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations.
Shimada H, Lu Q, Insinna-Kettenhofen C, Nagashima K, English MA, Semler EM, Mahgerefteh J, Cideciyan AV, Li T, Brooks BP, Gunay-Aygun M, Jacobson SG, Cogliati T, Westlake CJ, Swaroop A. Shimada H, et al. Among authors: semler em. Cell Rep. 2017 Jul 11;20(2):384-396. doi: 10.1016/j.celrep.2017.06.045. Cell Rep. 2017. PMID: 28700940 Free PMC article.
Akt Regulates a Rab11-Effector Switch Required for Ciliogenesis.
Walia V, Cuenca A, Vetter M, Insinna C, Perera S, Lu Q, Ritt DA, Semler E, Specht S, Stauffer J, Morrison DK, Lorentzen E, Westlake CJ. Walia V, et al. Dev Cell. 2019 Jul 22;50(2):229-246.e7. doi: 10.1016/j.devcel.2019.05.022. Epub 2019 Jun 13. Dev Cell. 2019. PMID: 31204173 Free PMC article.
LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8.
Allen RM, Michell DL, Cavnar AB, Zhu W, Makhijani N, Contreras DM, Raby CA, Semler EM, DeJulius C, Castleberry M, Zhang Y, Ramirez-Solano M, Zhao S, Duvall C, Doran AC, Sheng Q, Linton MF, Vickers KC. Allen RM, et al. Among authors: semler em. Nat Cell Biol. 2022 Dec;24(12):1701-1713. doi: 10.1038/s41556-022-01030-7. Epub 2022 Dec 6. Nat Cell Biol. 2022. PMID: 36474072 Free PMC article.
Elucidation of physico-chemical principles of high-density lipoprotein-small RNA binding interactions.
Michell DL, Allen RM, Cavnar AB, Contreras DM, Yu M, Semler EM, Massick C, Raby CA, Castleberry M, Ramirez MA, Zhu W, May-Zhang L, Ifrim A, Carr JJ, Terry JG, Schwendeman A, Davies SS, Sheng Q, Linton MF, Vickers KC. Michell DL, et al. Among authors: semler em. J Biol Chem. 2022 Jun;298(6):101952. doi: 10.1016/j.jbc.2022.101952. Epub 2022 Apr 18. J Biol Chem. 2022. PMID: 35447119 Free PMC article.
Darwin's finches treat their feathers with a natural repellent.
Cimadom A, Causton C, Cha DH, Damiens D, Fessl B, Hood-Nowotny R, Lincango P, Mieles AE, Nemeth E, Semler EM, Teale SA, Tebbich S. Cimadom A, et al. Among authors: semler em. Sci Rep. 2016 Oct 10;6:34559. doi: 10.1038/srep34559. Sci Rep. 2016. PMID: 27721475 Free PMC article.