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Hes1 triggers epithelial-mesenchymal transition (EMT)-like cellular marker alterations and promotes invasion and metastasis of nasopharyngeal carcinoma by activating the PTEN/AKT pathway.
Wang SC, Lin XL, Wang HY, Qin YJ, Chen L, Li J, Jia JS, Shen HF, Yang S, Xie RY, Wei F, Gao F, Rong XX, Yang J, Zhao WT, Zhang TT, Shi JW, Yao KT, Luo WR, Sun Y, Xiao D. Wang SC, et al. Among authors: chen l. Oncotarget. 2015 Nov 3;6(34):36713-30. doi: 10.18632/oncotarget.5457. Oncotarget. 2015. PMID: 26452025 Free PMC article.
MPC1 deficiency accelerates lung adenocarcinoma progression through the STAT3 pathway.
Zou H, Chen Q, Zhang A, Wang S, Wu H, Yuan Y, Wang S, Yu J, Luo M, Wen X, Cui W, Fu W, Yu R, Chen L, Zhang M, Lan H, Zhang X, Xie Q, Jin G, Xu C. Zou H, et al. Among authors: chen l, chen q. Cell Death Dis. 2019 Feb 15;10(3):148. doi: 10.1038/s41419-019-1324-8. Cell Death Dis. 2019. PMID: 30770798 Free PMC article.
Endoscopic surgery compared with intensity-modulated radiotherapy in resectable locally recurrent nasopharyngeal carcinoma: a multicentre, open-label, randomised, controlled, phase 3 trial.
Liu YP, Wen YH, Tang J, Wei Y, You R, Zhu XL, Li J, Chen L, Ling L, Zhang N, Zou X, Hua YJ, Chen YM, Chen L, Lu LX, Chen MY, Wen WP. Liu YP, et al. Among authors: chen l, chen ym, chen my. Lancet Oncol. 2021 Mar;22(3):381-390. doi: 10.1016/S1470-2045(20)30673-2. Epub 2021 Feb 15. Lancet Oncol. 2021. PMID: 33600761 Clinical Trial.
NEK4 kinase regulates EMT to promote lung cancer metastasis.
Ding NH, Zhang L, Xiao Z, Rong ZX, Li Z, He J, Chen L, Ou DM, Liao WH, Sun LQ. Ding NH, et al. Among authors: chen l. J Cell Mol Med. 2018 Dec;22(12):5877-5887. doi: 10.1111/jcmm.13857. Epub 2018 Sep 24. J Cell Mol Med. 2018. PMID: 30247800 Free PMC article.
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