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LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.
Barth J, Abou-El-Ardat K, Dalic D, Kurrle N, Maier AM, Mohr S, Schütte J, Vassen L, Greve G, Schulz-Fincke J, Schmitt M, Tosic M, Metzger E, Bug G, Khandanpour C, Wagner SA, Lübbert M, Jung M, Serve H, Schüle R, Berg T. Barth J, et al. Leukemia. 2019 Jun;33(6):1411-1426. doi: 10.1038/s41375-018-0375-7. Epub 2019 Jan 24. Leukemia. 2019. PMID: 30679800
Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation.
Schulz-Fincke J, Hau M, Barth J, Robaa D, Willmann D, Kürner A, Haas J, Greve G, Haydn T, Fulda S, Lübbert M, Lüdeke S, Berg T, Sippl W, Schüle R, Jung M. Schulz-Fincke J, et al. Among authors: barth j. Eur J Med Chem. 2018 Jan 20;144:52-67. doi: 10.1016/j.ejmech.2017.12.001. Epub 2017 Dec 6. Eur J Med Chem. 2018. PMID: 29247860
Correction: LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.
Barth J, Abou-El-Ardat K, Dalic D, Kurrle N, Maier AM, Mohr S, Schütte J, Vassen L, Greve G, Schulz-Fincke J, Schmitt M, Tosic M, Metzger E, Bug G, Khandanpour C, Wagner SA, Lübbert M, Jung M, Serve H, Schüle R, Berg T. Barth J, et al. Leukemia. 2019 Jun;33(6):1541. doi: 10.1038/s41375-019-0415-y. Leukemia. 2019. PMID: 30837671
NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells.
Jayavelu AK, Müller JP, Bauer R, Böhmer SA, Lässig J, Cerny-Reiterer S, Sperr WR, Valent P, Maurer B, Moriggl R, Schröder K, Shah AM, Fischer M, Scholl S, Barth J, Oellerich T, Berg T, Serve H, Frey S, Fischer T, Heidel FH, Böhmer FD. Jayavelu AK, et al. Among authors: barth j. Leukemia. 2016 Feb;30(2):473-83. doi: 10.1038/leu.2015.234. Epub 2015 Aug 26. Leukemia. 2016. PMID: 26308771
Position statement of the GMA committee "teaching evaluation".
Haverkamp N, Barth J, Schmidt D, Dahmen U, Keis O, Raupach T. Haverkamp N, et al. Among authors: barth j. GMS J Med Educ. 2024 Apr 15;41(2):Doc19. doi: 10.3205/zma001674. eCollection 2024. GMS J Med Educ. 2024. PMID: 38779701 Free PMC article.
Unconventional Band Structure via Combined Molecular Orbital and Lattice Symmetries in a Surface-Confined Metallated Graphdiyne Sheet.
Piquero-Zulaica I, Hu W, Seitsonen AP, Haag F, Küchle J, Allegretti F, Lyu Y, Chen L, Wu K, El-Fattah ZMA, Aktürk E, Klyatskaya S, Ruben M, Muntwiler M, Barth JV, Zhang YQ. Piquero-Zulaica I, et al. Among authors: barth jv. Adv Mater. 2024 May 19:e2405178. doi: 10.1002/adma.202405178. Online ahead of print. Adv Mater. 2024. PMID: 38762788
Why Do Some Lineages Radiate While Others Do Not? Perspectives for Future Research on Adaptive Radiations.
De-Kayne R, Schley R, Barth JMI, Campillo LC, Chaparro-Pedraza C, Joshi J, Salzburger W, Van Bocxlaer B, Cotoras DD, Fruciano C, Geneva AJ, Gillespie R, Heras J, Koblmüller S, Matthews B, Onstein RE, Seehausen O, Singh P, Svensson EI, Salazar-Valenzuela D, Vanhove MPM, Wogan GOU, Yamaguchi R, Yoder AD, Cerca J. De-Kayne R, et al. Among authors: barth jmi. Cold Spring Harb Perspect Biol. 2024 May 1:a041448. doi: 10.1101/cshperspect.a041448. Online ahead of print. Cold Spring Harb Perspect Biol. 2024. PMID: 38692838
Risk factors and prevalence of ramp lesions in ACL ruptures: An analysis from the registry of the Francophone Arthroscopic Society.
Lambrey PJ, Fayard JM, Graveleau N, Toanen C, Noailles T, Letartre R, Barth J, Cavaignac E; Francophone Society of Arthroscopy ACL Registry Study Group; Bouguennec N, Thaunat M. Lambrey PJ, et al. Among authors: barth j. Knee Surg Sports Traumatol Arthrosc. 2024 Apr 24. doi: 10.1002/ksa.12194. Online ahead of print. Knee Surg Sports Traumatol Arthrosc. 2024. PMID: 38655742
1,574 results